{"title":"Effect of mitochondrial pathway on hepatic ischemia-reperfusion injury","authors":"Jie Lin, Z. Zeng","doi":"10.3760/CMA.J.ISSN.1007-8118.2020.01.018","DOIUrl":null,"url":null,"abstract":"Hepatic ischemia-reperfusion injury is often occurred during the hepatobiliary surgery, and is closely correlated with postoperative of liver function recovery and prognosis. Although the mechanisms of hepatic ischemia-reperfusion injury are complex, mitochondrial structural dysfunction is an important event for hepatic ischemia-reperfusion injury. This review summarized the current mechanism of hepatic ischemia-reperfusion injury, and with a focus on mitigating its damage through the mitochondrial autophagy and apoptosis pathway. \n \nKey words: \nReperfusion injury; Liver; Mitochondria","PeriodicalId":10021,"journal":{"name":"中华肝胆外科杂志","volume":"26 1","pages":"69-72"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华肝胆外科杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1007-8118.2020.01.018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Hepatic ischemia-reperfusion injury is often occurred during the hepatobiliary surgery, and is closely correlated with postoperative of liver function recovery and prognosis. Although the mechanisms of hepatic ischemia-reperfusion injury are complex, mitochondrial structural dysfunction is an important event for hepatic ischemia-reperfusion injury. This review summarized the current mechanism of hepatic ischemia-reperfusion injury, and with a focus on mitigating its damage through the mitochondrial autophagy and apoptosis pathway.
Key words:
Reperfusion injury; Liver; Mitochondria
期刊介绍：
Chinese Journal of Hepatobiliary Surgery is an academic journal organized by the Chinese Medical Association and supervised by the China Association for Science and Technology, founded in 1995. The journal has the following columns: review, hot spotlight, academic thinking, thesis, experimental research, short thesis, case report, synthesis, etc. The journal has been recognized by Beida Journal (Chinese Journal of Humanities and Social Sciences).
Chinese Journal of Hepatobiliary Surgery has been included in famous databases such as Peking University Journal (Chinese Journal of Humanities and Social Sciences), CSCD Source Journals of China Science Citation Database (with Extended Version) and so on, and it is one of the national key academic journals under the supervision of China Association for Science and Technology.
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