A Review Of The Methods And Approaches For Integrating Genetics And Metabolomics Into Personalized Nutrition

Q3 Pharmacology, Toxicology and Pharmaceutics Journal of Pharmaceutical Negative Results Pub Date : 2023-04-03 DOI:10.47750/pnr.2023.14.02.447
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Abstract

Personalized nutrition is emerging as a promising approach to optimize health outcomes by accounting for individual genetic and metabolic differences. This review examines the current methods and approaches for integrating genetics and metabolomics into personalized nutrition strategies. We discuss the importance of understanding an individual's genetic makeup, including single nucleotide polymorphisms (SNPs), and their effects on nutrient metabolism and health outcomes. Additionally, we explore the role of metabolomics in elucidating individual metabolic profiles and identifying biomarkers for personalized dietary interventions. We also discuss the application of computational and machine learning techniques in data integration and analysis, as well as the ethical and regulatory considerations surrounding personalized nutrition. The ultimate goal is to provide a comprehensive overview of the current state of the field and identify future research opportunities to improve the implementation of personalized nutrition for disease prevention and overall health promotion.
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将遗传学和代谢组学整合到个性化营养中的方法和途径综述
通过考虑个体遗传和代谢差异,个性化营养正在成为一种有希望的优化健康结果的方法。本文综述了目前将遗传学和代谢组学整合到个性化营养策略中的方法和途径。我们讨论了理解个体基因组成的重要性,包括单核苷酸多态性(snp),以及它们对营养代谢和健康结果的影响。此外,我们还探讨了代谢组学在阐明个体代谢谱和识别个性化饮食干预的生物标志物方面的作用。我们还讨论了计算和机器学习技术在数据集成和分析中的应用,以及围绕个性化营养的伦理和监管考虑。最终目标是对该领域的现状提供一个全面的概述,并确定未来的研究机会,以改进个性化营养的实施,以预防疾病和促进整体健康。
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