Anomalies in the development of the tracheobronchial tree (clinical case)

Q4 Biochemistry, Genetics and Molecular Biology Sibirskii nauchnyi meditsinskii zhurnal Pub Date : 2023-08-31 DOI:10.18699/ssmj20230417
E. Semichev, N. Medvedeva
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Abstract

According to the International Classification of Diseases the trachebronchial tree (TBT) anomalies are grouped into class XVII “Congenital anomalies (malformations), deformities and chromosomal disorders” (Q30–Q34, namely Q32.1 – “Other malformations of the trachea”).This paper presents a clinical case of congenital anomaly of TBT. Patient M., 18 years old, diagnosis of ICD-10 J90 Pleural effusion, not classified elsewhere, was referred from the pulmonology department to perform bronchoscopy for differential diagnosis with pulmonary tuberculosis. When the device was passed through the trachea, in the lower third towards the right main bronchus, a diverticuloid protrusion of the tracheal wall with deformation of the cartilaginous ring was found.Results and discussions. After examination, the conclusion was formed: Anomaly in the development of the lower third of the trachea (reduced tracheal bronchus on the right). Anomalies in the development of TBT are an extremely rare pathology, the pathology we describe is called “tracheal bronchus”. The tracheal bronchus, the rarest malformation of TBT with a frequency of no more than 1–2 % of cases, is the result of dysontogenesis. It is usually located on the right side of the trachea and may end blindly in the form of a diverticulum. In our description, there is no other anomaly of the TBT, so it can be attributed to the supernumerary variant of the tracheal bronchus. When anomalies in the development of TBT are detected, it is necessary to carry out differential diagnostics with tracheal diverticula, in which only its membranous part suffers.Conclusions. The clinical case we are describing refers to a supernumerary variant of the tracheal bronchus and requires the additional use of high-tech verification methods. We do not exclude that the environmental factors in the city of Zheleznogorsk could be the cause of its development.
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气管支气管树发育异常(临床病例)
根据国际疾病分类,气管支气管树(TBT)异常分为第十七类“先天性异常(畸形)、畸形和染色体疾病”(Q30–Q34,即Q32.1–“其他气管畸形”)。本文报告一例先天性TBT异常的临床病例。患者M,18岁,诊断为ICD-10 J90胸腔积液,未在其他地方分类,从肺科转诊进行支气管镜检查,以鉴别诊断为肺结核。当该装置穿过气管时,在朝向右主支气管的下三分之一处,发现气管壁的憩室样突起,软骨环变形。结果和讨论。经检查,得出结论:气管下三分之一发育异常(右侧气管支气管缩小)。TBT发展异常是一种极为罕见的病理,我们所描述的病理被称为“气管支气管”。气管支气管是TBT最罕见的畸形,发生率不超过1-2%,是发育不良的结果。它通常位于气管的右侧,可能会以憩室的形式盲目结束。在我们的描述中,TBT没有其他异常,因此可以将其归因于气管支气管的多生变异。当检测到TBT发展异常时,有必要对气管憩室进行鉴别诊断,因为只有其膜部受损。结论。我们所描述的临床病例是指气管支气管的一种多余变体,需要额外使用高科技验证方法。我们不排除Zheleznogorsk市的环境因素可能是其发展的原因。
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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
54
审稿时长
12 weeks
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