Prevalence and biopsychosocial factors associated with treatment adherence among people with epilepsy in a tertiary care hospital in Riyadh, Saudi Arabia

IF 1.2 4区医学 Q4 CLINICAL NEUROLOGY Neurosciences Pub Date : 2022-04-01 DOI:10.17712/nsj.2022.2.20210142

Amani S Almwled, Abdulkarim O. Almuhaydili, S. M. Altamimi, Muhannad A Alzahrani, Rodhan K Alnahdi, Saad B Almotairi, Bandar N. Aljafen, F. Alosaimi

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引用次数: 2

Abstract

Objectives: To identify the magnitude of treatment adherence among people with epilepsy (PWE) and the impact of sociodemographic, medical and psychosocial factors on treatment adherence. Methods: A quantitative cross-sectional observational study was performed based on data collected from adult patients attending the epilepsy clinic, King Saud University Medical City, Riyadh, Saudi Arabia. Patients completed paper-based questionnaires including a sociodemographic, cultural, psychiatric history and medical history sections. In addition to that we evaluated treatment adherence by visual-analogue scale (VAS), depressive symptoms by PHQ-9, anxiety symptoms by GAD7, physical symptoms by PHQ-15, attachment style by ECR16 and cognitive impairment by MOCA. Results: A total of 207 patients participated, with a mean age of 34 years;.53.6% were female. The mean patient-reported adherence to their treatment regimen was 81.6%±18.4%. Univariate analysis revealed statistically significant negative associations between depression, anxiety and physical symptoms and treatment adherence. However, multiple linear regression analysis only showed physical symptoms to be a significant predictor for epilepsy medication adherence. Conclusion: Somatic (physical) complaints could be important predictors of treatment adherence in (PWE). This study is one of the first to suggest the importance of targeting physical symptoms in screening and intervention approaches to improve Antiepileptic drugs (AEDs) adherence.

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沙特阿拉伯利雅得一家三级护理医院癫痫患者的患病率和与治疗依从性相关的生物心理社会因素

目的：确定癫痫患者（PWE）的治疗依从性程度，以及社会人口统计学、医学和心理社会因素对治疗依从性的影响。方法：根据从沙特阿拉伯利雅得沙特国王大学医学城癫痫诊所的成年患者中收集的数据进行定量横断面观察性研究。患者填写了纸质问卷，包括社会人口、文化、精神病史和病史部分。此外，我们通过视觉模拟量表（VAS）评估了治疗依从性，通过PHQ-9评估了抑郁症状，通过GAD7评估了焦虑症状，通过PHQ-15评估了身体症状，通过ECR16评估了依恋风格，通过MOCA评估了认知障碍。结果：共有207名患者参与，平均年龄34岁；。女性占53.6%。患者对治疗方案的平均依从性为81.6%±18.4%。单变量分析显示，抑郁、焦虑和身体症状与治疗依从性之间存在统计学上显著的负相关。然而，多元线性回归分析仅显示身体症状是癫痫药物依从性的重要预测因素。结论：躯体（身体）主诉可能是PWE患者治疗依从性的重要预测因素。这项研究是首次提出针对身体症状的筛查和干预方法的重要性，以提高抗癫痫药物（AED）的依从性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurosciences 医学-临床神经学

CiteScore

1.40

自引率

0.00%

发文量

审稿时长

4.5 months

期刊介绍： Neurosciences is an open access, peer-reviewed, quarterly publication. Authors are invited to submit for publication articles reporting original work related to the nervous system, e.g., neurology, neurophysiology, neuroradiology, neurosurgery, neurorehabilitation, neurooncology, neuropsychiatry, and neurogenetics, etc. Basic research withclear clinical implications will also be considered. Review articles of current interest and high standard are welcomed for consideration. Prospective workshould not be backdated. There are also sections for Case Reports, Brief Communication, Correspondence, and medical news items. To promote continuous education, training, and learning, we include Clinical Images and MCQ’s. Highlights of international and regional meetings of interest, and specialized supplements will also be considered. All submissions must conform to the Uniform Requirements.