Is Forced Coughing Effective in Reducing Pain During Cervical Biopsy?: A systematic review and meta-analysis.

Q3 Medicine Sultan Qaboos University Medical Journal Pub Date : 2023-11-01 Epub Date: 2023-11-30 DOI:10.18295/squmj.5.2023.026

Yassamine Ouerdane, Aya Abd Elmegeed, Mohammed Tarek, Imane Bakhtaoui, Ahmed K Awad, Nihal Al Riyami, Ahmed Saad

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Abstract

This review aimed to compare the potential analgesic effect of forced coughing (FC) with that of local anaesthetics (LA) or placebo during cervical biopsy. A total of 5 electronic databases-Scopus, PubMed, Web of Science, Cochrane Library and Google Scholar-were systematically searched from inception till March 2021. Data were extracted from 6 randomised controlled trials and analysed. During cervical biopsy, the overall effect favoured LA over FC (mean difference [MD] = 1.06, 95% confidence interval [CI]: 0.58 to 1.54; P <0.0001). Compared to no pain management, pooled data were comparable between the two groups (MD = -1.2, 95% CI: -3.35 to 0.94; P = 0.27). Procedure duration was significantly longer in the LA group than in the FC group (MD = -1.94, 95% CI: -2.47 to -1.41; P <0.00001). FC and LA are both useful pain-lowering modalities during cervical biopsy, depending on the setting and their availability.

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宫颈活检时强迫咳嗽是否有效减轻疼痛?

我们的目的是比较宫颈活检时强迫咳嗽(FC)技术与局部麻醉(LA)或安慰剂的潜在镇痛效果。从成立到2021年3月，我们系统地检索了5个电子数据库;Scopus, PubMed, Web of Science, Cochrane Library, b谷歌Scholar。从6个随机对照试验中提取数据，并使用Review Manager软件进行分析。在宫颈活检中，LA组总体效果优于FC组(MD =1.06;95% CI [0.58 ~ 1.54];P < 0.0001)。另一方面，与无疼痛管理相比，两组间的汇总数据具有可比性(MD = -1.2;95% CI [-3.35 ~ 0.94];P = 0.27)。LA组手术时间明显长于FC组(MD = -1.94;95% CI [-2.47 ~ - 1.41];P < 0.00001)。根据设置和可用性，FC和LA在宫颈活检期间似乎是有用的镇痛方式。建议进一步研究。关键词:宫颈活检;阴道镜;强迫咳嗽;疼痛。

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