Lucija Hok, Davorin Šakić, Valerije Vrček, Robert Vianello
{"title":"Farmaceutski značaj procesa stereoizomerizacije","authors":"Lucija Hok, Davorin Šakić, Valerije Vrček, Robert Vianello","doi":"10.15255/kui.2022.027","DOIUrl":null,"url":null,"abstract":"Investigation of the stereoisomerisation process is of the utmost importance in pharmaceutical chemistry and biomedicine. Different isomers can exhibit significant differences when interacting with biological macromolecules, which may result in their modified pharmacokinetic and phar - macodynamic properties, thereby showing different therapeutic and undesirable effects. Although there are numerous examples illustrating the importance of stereochemistry, this article presents an overview of the most significant and representative cases in pharmacy.","PeriodicalId":0,"journal":{"name":"","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15255/kui.2022.027","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Investigation of the stereoisomerisation process is of the utmost importance in pharmaceutical chemistry and biomedicine. Different isomers can exhibit significant differences when interacting with biological macromolecules, which may result in their modified pharmacokinetic and phar - macodynamic properties, thereby showing different therapeutic and undesirable effects. Although there are numerous examples illustrating the importance of stereochemistry, this article presents an overview of the most significant and representative cases in pharmacy.
分享
京公网安备 11010802042870号
京ICP备2023020795号-1
求助内容：
应助结果提醒方式：
扫码关注我们
