Solitary plasmacytoma of rib: a rare presentation

Abstract

Plasmacytoma is a localized collection of neoplastic plasma cells presenting either as a solitary lesion or a manifestation of multiple myeloma.1 The International Myeloma Working Group has defined a diagnostic criteria for Solitary Plasmacytoma of Bone which requires all the following to be fulfilled: (i) biopsy‒proven solitary lesion of bone or soft tissue with evidence of clonal plasma cells, (ii) Normal bone marrow with no evidence of clonal plasma cells, (iii) Normal skeletal survey and MRI (or CT) of the spine and pelvis (except for the primary solitary lesion), and (iv) Absence of end‒organ damage such as hypercalcemia, renal insufficiency, anemia, or bone lesions (CRAB) that can be attributed to a lymphoplasma cell proliferative disorder.2