Beat-to-beat heart rate and QT interval variability in patients undergoing coronary artery bypass graft surgery

S. Frljak, V. Avbelj, R. Trobec, B. Geršak
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引用次数: 3

Abstract

Non-uniform recovery of myocardial excitability may be essential in triggering malignant ventricular tachycardia in patients after cardiac surgery. Beat-to-beat heart rate and QT interval variability was investigated in 27 patients scheduled for elective coronary artery bypass graft surgery (CABG) and 20 control subjects. 35 channel ECG was recorded for 6 minutes, followed by off line computer analysis. Heart rate interval duration, RR SD, QT SD and power spectra of RR variability were computed from 256-second stable heart rate and QT interval series using MECG software. Study showed that CABG caused increased QT interval variability in face of nearly constant or slowly changing heart rate, suggesting a loss of autonomic coupling between heart rate and ventricular repolarization for sympathovagal modulation.
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冠状动脉搭桥手术患者的单次心率和QT间期变异性
心肌兴奋性的不均匀恢复可能是引发心脏手术后患者恶性室性心动过速的必要条件。研究了27例计划择期冠状动脉搭桥手术(CABG)患者和20例对照者的次搏动心率和QT间期变异性。记录35通道心电图6分钟,然后进行计算机离线分析。采用MECG软件计算256秒稳定心率和QT间期序列的心率间期持续时间、RR SD、QT SD和RR变异性的功率谱。研究表明,面对几乎恒定或缓慢变化的心率,冠状动脉搭桥导致QT间期变异性增加,提示心率和心室复极之间的自主耦合丧失了交感病理迷走神经调节。
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