HANTAVIRUS CARDIOPULMONARY SYNDROME IN RIBEIRÃO PRETO, BRAZIL, 2010-2011

G. G. Figueiredo, M. D. Pádua, G. S. Júnior, A. M. Machado, M. Romero, Daniela Leitão Delsin, A. Carvalho, S. J. Badra, L. T. Figueiredo
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Abstract

Cardiopulmonary Syndrome (HCPS) is a severe disease caused by Hantaviruses. In the present study, we have analyzed sera of 62 HCPS suspected cases from the region of Ribeirao Preto, Sao Paulo, in the period of 2010-2011. Clinical samples of twelve patients were positive, based on both RT-PCR and IgM-ELISA. Hantavirus-infected patients included 8 males and 4 females, 16-57 years old, 3 of whom were rural workers (25%) and one of them related direct contact with wild rodents. The majority of the other patients (75%) lived in the periphery of cities and reported the presence of rodents in their homes. The case fatality ratio of these 12 HCPS cases was 41.6%. Our results confirm that hantaviruses are endemic, with occurrence of HCPS and fatalities, every year, in the region of Ribeirao Preto. More educational and preventive measures are necessary in order to prevent human infections by hantavirus in the region, and other parts of Brazil. DOI:  http://dx.doi.org/10.17525/vrrjournal.v16i1-2.54
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2010-2011年巴西ribeirÃo普雷图的汉坦病毒心肺综合征
心肺综合征(HCPS)是由汉坦病毒引起的一种严重疾病。在本研究中,我们分析了2010-2011年期间来自圣保罗Ribeirao Preto地区的62例HCPS疑似病例的血清。12例患者临床标本RT-PCR和IgM-ELISA均为阳性。汉坦病毒感染患者男8例,女4例,年龄16 ~ 57岁,其中农民工3例(25%),1例与野生啮齿动物有直接接触。其他大多数患者(75%)居住在城市外围,并报告家中有啮齿动物。12例HCPS病死率为41.6%。我们的研究结果证实,汉坦病毒是一种地方性疾病,每年在里贝罗普雷图地区都会发生HCPS和死亡病例。有必要采取更多的教育和预防措施,以防止该地区和巴西其他地区的人感染汉坦病毒。DOI: http://dx.doi.org/10.17525/vrrjournal.v16i1 - 2.54
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