{"title":"Gastrointestinal ulceration in dogs with portosystemic shunt","authors":"J. Frymus, P. Trębacz, M. Galanty","doi":"10.21521/mw.6786","DOIUrl":null,"url":null,"abstract":"Portosystemic shunt (PSS) in dogs is a common abnormality in which blood from the intestines bypasses the liver flowing directly to the systemic circulation through an aberrant vessel. The lack of hepatic detoxication can lead to a fatal outcome. Treatment of choice is a surgical occlusion of the shunt. Gastrointestinal ulceration/ erosion (GUE) has been described as one of the numerous clinical consequences of PSS, As these lesions are a severe complication, and seem to be underestimated, this review presents the current knowledge about GUE in dogs with PSS. Although the pathogenesis of these lesions is not clear and experimental data are scarce, we conclude that proton pump inhibitors should be administered pre- and postoperatively to dogs with PSS to reduce the incidence of GUE and thus increase the recovery rate.","PeriodicalId":49017,"journal":{"name":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medycyna Weterynaryjna-Veterinary Medicine-Science and Practice","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.21521/mw.6786","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 1
Abstract
Portosystemic shunt (PSS) in dogs is a common abnormality in which blood from the intestines bypasses the liver flowing directly to the systemic circulation through an aberrant vessel. The lack of hepatic detoxication can lead to a fatal outcome. Treatment of choice is a surgical occlusion of the shunt. Gastrointestinal ulceration/ erosion (GUE) has been described as one of the numerous clinical consequences of PSS, As these lesions are a severe complication, and seem to be underestimated, this review presents the current knowledge about GUE in dogs with PSS. Although the pathogenesis of these lesions is not clear and experimental data are scarce, we conclude that proton pump inhibitors should be administered pre- and postoperatively to dogs with PSS to reduce the incidence of GUE and thus increase the recovery rate.
期刊介绍：
"Medycyna Weterynaryjna" publishes various types of articles which are grouped in the following editorial categories: reviews, original studies, scientific and professional problems, the history of veterinary medicine, posthumous memoirs, as well as chronicles that briefly relate scientific advances and developments in the veterinary profession and medicine. The most important are the first two categories, which are published with short summaries in English. Moreover, from 2001 the editors of "Medycyna Weterynaryjna", bearing in mind market demands, has also started publishing entire works in English. Since 2008 the periodical has appeared in an electronic version. The following are available in this version: summaries of studies published from 1999 to 2005, full versions of all the studies published in the years 2006-2011 (in pdf files), and full versions of the English studies published in the current year (pdf). Only summaries of the remaining studies from the current year are available. In accordance with the principles accepted by the editors, the full versions of these texts will not be made available until next year.
All articles are evaluated twice by leading Polish scientists and professionals before they are considered for publication. For years now "Medycyna Weterynaryjna" has maintained a high standard thanks to this system. The review articles are actually succinct monographs dealing with specific scientific and professional problems that are based on the most recent findings. Original works have a particular value, since they present research carried out in Polish and international scientific centers.
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