Characteristics of patients with diagnosed chronic fungal rhinosinusitis surgically treated in the past five years

IF 0.2 4区 医学 Q4 MEDICINE, GENERAL & INTERNAL Srpski arhiv za celokupno lekarstvo Pub Date : 2023-01-01 DOI:10.2298/sarh211016053b
Maja M Buljčik-Čupić, S. Savovic, S. Lemajic-Komazec, D. Dragičević, T. Tesic, I. Sivčev
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Abstract

Introduction/Objective Fungal rhinosinusitis comprises of a wide range of immune-pathological responses, including invasive, chronic, granulomatous, and allergic diseases. Aim of this study was to determine total number of patients, their characteristics, frequency of symptoms, the manner of disease manifestation and the success of therapy. Methods Study included 21 patients with diagnosis FRS made according to the 2012 EPOS guidelines. Results Based on VAS(visual analogue scale), feeling of localized pressure, ie. facial pain was dominant in 9.57 ? 0.98, than the secretion from the nose is 8.14 ? 1.62, problem of the breathing on the nose in 6.67 ? 3.25, while reduction the sense of smell was in 2.14 ? 3.00. T-test showed there is a statistically significant difference between mucosal changes on the diseased and healthy sides of the patient's face (p <0.0001). Intraoperative in 18 (85.71%) patients only one sinus was affected. The most commonly affected sinus was maxillary, in 13 (54.17%) cases, followed by sphenoid sinus in 5 (20.83%) cases. As a cause of rhinosinusitis Aspergillus was proven in 12 (57.14%) patients. Conclusion The dominant symptom of patients with fungal rhinosinusitis was localized pain / pressure in the area of the affected sinus. Endoscopically, on the side of the affected sinus, the pathological mucosa with thick, pithy, mucous secretion dominated. The maxillary sinus is primarily unilaterally affected, in more than half of the patients. Aspergillus has been proven to be the most common cause of rhinosinusitis.
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近五年来外科治疗的慢性真菌性鼻窦炎患者的特点
真菌性鼻窦炎包括广泛的免疫病理反应,包括侵袭性、慢性、肉芽肿性和过敏性疾病。本研究的目的是确定患者的总数,他们的特点,症状的频率,疾病表现的方式和治疗的成功。方法纳入21例根据2012年EPOS指南诊断为FRS的患者。结果根据视觉模拟评分(VAS),局部压感(即:面部疼痛在9.57 ?0.98,比鼻分泌物8.14 ?1.62, 6.67中鼻子呼吸的问题?3.25,而嗅觉的减少在2.14 ?3.00. t检验显示,患者患病侧与健康侧面部粘膜变化差异有统计学意义(p <0.0001)。术中18例(85.71%)患者仅1个鼻窦受累。上颌窦最常见,13例(54.17%);蝶窦次之,5例(20.83%)。12例(57.14%)鼻鼻窦炎的病因为曲霉菌。结论真菌性鼻窦炎患者的主要症状为鼻窦局部疼痛/压迫。内镜下,在受累鼻窦一侧,病理黏膜以厚、髓质、粘液分泌为主。上颌窦主要是单侧受累,超过一半的患者。曲霉已被证明是鼻窦炎最常见的原因。
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来源期刊
Srpski arhiv za celokupno lekarstvo
Srpski arhiv za celokupno lekarstvo MEDICINE, GENERAL & INTERNAL-
CiteScore
0.40
自引率
50.00%
发文量
104
审稿时长
4-8 weeks
期刊介绍: Srpski Arhiv Za Celokupno Lekarstvo (Serbian Archives of Medicine) is the Journal of the Serbian Medical Society, founded in 1872, which publishes articles by the members of the Serbian Medical Society, subscribers, as well as members of other associations of medical and related fields. The Journal publishes: original articles, communications, case reports, review articles, current topics, articles of history of medicine, articles for practitioners, articles related to the language of medicine, articles on medical ethics (clinical ethics, publication ethics, regulatory standards in medicine), congress and scientific meeting reports, professional news, book reviews, texts for "In memory of...", i.e. In memoriam and Promemoria columns, as well as comments and letters to the Editorial Board. All manuscripts under consideration in the Serbian Archives of Medicine may not be offered or be under consideration for publication elsewhere. Articles must not have been published elsewhere (in part or in full).
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