Glycomics & Infection Markers

Arun Padala
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Abstract

The biosynthesis of glycan depends on a number of profoundly competitive forms including glycosyl transferase. Glycosylation is subsequently profoundly delicate to the biochemical environment and has been ensnared in numerous maladies counting cancer. As of late, intrigued in profiling the glycome has expanded due to the potential of glycans for illness markers. In this respect, mass spectrometry is rising as a capable procedure for profiling the glycome. Worldwide glycan profiling of human serum based on mass spectrometry has as of now driven to a few possibly promising markers for a few sorts of cancer and illnesses.
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糖组学和感染标志物
聚糖的生物合成依赖于包括糖基转移酶在内的许多具有高度竞争性的形式。随后,糖基化对生化环境非常敏感,并在包括癌症在内的许多疾病中陷入困境。最近,由于聚糖作为疾病标志物的潜力,对分析聚糖的兴趣已经扩大。在这方面,质谱分析作为一种分析血糖的有效方法正在兴起。目前,世界范围内基于质谱法的人类血清聚糖谱分析已经为几种癌症和疾病提供了一些可能有前途的标记物。
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