TAVI in bicuspid aortic valve

I. Dimitrova, J. Jorgova, P. Simeonov, H. Angelov, D. Trendafilova
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Abstract

Transcatheter aortic valve implantation (TAVI) is an established choice for the treatment of severe aortic stenosis (AS) in patients who are deemed inoperable or at high surgical risk. There are limited data for the safety and effi cacy of the method in patients with bicuspid aortic valve (BAV), the most common congenital valve defect. Patients with BAV were excluded from randomized clinical trials (RCTs), comparing TAVI to surgery due to the heterogeneous anatomy of this nosological unit and concerns about unsatisfactory procedural and clinical outcomes after TAVI. With the improvement of the design of the new generations devices, with the growing technical experience of the teams and the progress in the imaging techniques, better results and fewer complications are observed, which could be a prerequisite for expanding the indications for TAVI in patients with BAV. This review presents TAVI treatment options for patients with BAV, the results of available registers in terms of safety and effi cacy of the procedure, and future perspectives.
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二尖瓣主动脉瓣TAVI
经导管主动脉瓣植入术(TAVI)是治疗严重主动脉瓣狭窄(AS)的一种既定选择,这些患者被认为不能手术或手术风险高。对于双尖瓣主动脉瓣(BAV)患者,该方法的安全性和有效性数据有限,这是最常见的先天性瓣膜缺陷。BAV患者被排除在比较TAVI与手术的随机临床试验(rct)之外,因为该分科单位的解剖结构不均匀,并且担心TAVI后的手术和临床结果不满意。随着新一代器械设计的完善,团队技术经验的积累,影像技术的进步,效果更好,并发症更少,这可能是扩大BAV患者TAVI适应证的前提。这篇综述介绍了BAV患者的TAVI治疗方案,在安全性和有效性方面的现有登记结果,以及未来的展望。
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CiteScore
0.10
自引率
0.00%
发文量
40
审稿时长
12 weeks
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