Botulinum toxin: Non cosmetic and off-label dermatological uses

Ali S. Al-Ghamdi, Noah Alghanemy, Hanan Joharji, Dhafer Al-Qahtani, Hasan Alghamdi
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引用次数: 11

Abstract

Botulinum toxin (BT-A) is a neurotoxin which is produced by the Gram-positive anaerobic bacterium Clostridium botulinum. The efficacy of Botulinum toxin in treating hyperhidrosis and the glabellar lines is well known and FDA approved.

Because BT-A inhibits the release of acetylcholine and many other neurotransmitters such as norepinephrine and substance P at the level of nerve ending, this toxin has been used to treat a lot of dermatological disorders which are thought to be triggered by these neurotransmitters.

In this article we are discussing the medical off-label uses of BT-A in dermatology.

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肉毒杆菌毒素:非化妆品和标签外的皮肤病学用途
肉毒杆菌毒素(BT-A)是一种由革兰氏阳性厌氧菌肉毒杆菌产生的神经毒素。肉毒杆菌毒素在治疗多汗症和眉间线的疗效是众所周知的,FDA批准。由于BT-A在神经末梢水平上抑制乙酰胆碱和许多其他神经递质的释放,如去甲肾上腺素和P物质,这种毒素已被用于治疗许多被认为是由这些神经递质引发的皮肤病。在这篇文章中,我们正在讨论BT-A在皮肤科的医疗标签外使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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17
审稿时长
16 weeks
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