Curcuminoid Prevents Protein Oxidation but not Lipid Peroxidation in Exercise Induced Muscle Damage Mouse

Abstract

Oxidative stress is believed as underlined mechanism of exercise induced muscle damage. This study was aimed to investigate curcuminoid effect on protein oxidation and lipid peroxidation muscle of exercised induced model. Adult male healthy mice were used as experiment models, grouped in to curcuminoid treated, placebo (corn oil only treated) and untreated group. Protein carbonyl level was significantly lower in curcuminoid treated group compared with untreated group (p =0.003). In the contrary, the malondialdehyde level was not significantly different between those groups (p = 0.092).