Recurrent cervical chordoma: A case illustration

Jun Liu, Bin Ni, Ning Xie, Huajiang Chen, Fei Wang, Zhuangchen Zhu, Peida Lin
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Abstract

A case is described of multi-recurrent cervical chordoma in a man over a 5 year period. The clinical features were of progressive spinal cord compression. The authors report a chordoma at C4 that recurred 3 times in five years. The patient underwent four operations and suffered distant metastases. This case confirms that thorough resection of the tumor during the first surgery and post-operative adjuvant treatment are the best assurance of a good prognosis with a chordoma. Multiple surgeries can stimulate biological activity of a chordoma and make its recurrence and distant metastases much more likely. The authors discuss the diagnosis, surgical treatment and the relationship between the histopathological changes and malignancy of a spinal chordoma after four operations. To our knowledge, this represents the first report of a 4th surgery for cervical chordoma.

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复发性颈脊索瘤1例
一个病例描述了多复发宫颈脊索瘤在一个男人超过5年的时间。临床表现为进行性脊髓压迫。作者报告了一例C4脊索瘤在5年内复发3次。患者接受了四次手术并出现了远处转移。本病例证实,在第一次手术中彻底切除肿瘤和术后辅助治疗是脊索瘤预后良好的最佳保证。多次手术可刺激脊索瘤的生物活性,使其更容易复发和远处转移。作者讨论了脊髓瘤四次手术后的诊断、手术治疗及组织病理学变化与恶性肿瘤的关系。据我们所知,这是颈椎脊索瘤第4次手术的第一份报告。
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