CD36, a signaling receptor and fatty acid transporter that regulates immune cell metabolism and fate

Yiliang Chen, Jue Zhang, W. Cui, R. Silverstein
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引用次数: 76

Abstract

CD36 functions as both a signaling receptor and fatty acid transporter in various immune and non-immune cells. This review summarizes how its dual functions determine immune cell functions and fates, which contribute to common diseases including atherosclerosis and tumor progression.
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CD36,一种调节免疫细胞代谢和命运的信号受体和脂肪酸转运体
CD36在多种免疫和非免疫细胞中既是信号受体又是脂肪酸转运蛋白。本文综述了它的双重功能如何决定免疫细胞的功能和命运,并在动脉粥样硬化和肿瘤进展等常见疾病中发挥作用。
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