Excretory-Secretory Antigens of Trypanosoma cruzi Are Potentially Useful for Serodiagnosis of Chronic Chagas' Disease

M. Nakazawa, D. S. Rosa, V. Pereira, Milena O. Moura, V. C. Furtado, W. Souza, M. D. N. D. S. Barros, F. Abath, Y. Gomes
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引用次数: 39

Abstract

ABSTRACT The reactivities of sera from chronic chagasic patients against the trypomastigote excreted-secreted antigens (TESA) of Trypanosoma cruzi strains with different biodemes were analyzed by TESA-blot and TESA–enzyme-linked immunosorbent assay (ELISA). Although both tests presented high sensitivity and specificity, TESA-ELISA is more appropriate for screening a larger number of samples.
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克氏锥虫排泄-分泌抗原在慢性恰加斯病血清诊断中的潜在价值
采用TESA-blot和TESA酶联免疫吸附试验(ELISA)分析慢性血吸虫患者血清对不同生物组克氏锥虫菌株的胰蛋白酶体分泌抗原(TESA)的反应性。虽然两种检测方法都具有较高的灵敏度和特异性,但TESA-ELISA更适合于筛选大量的样品。
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