Tremor recording and analysis as a tool for target localisation in thalamotomy and DBS for tremor

H. Journée, D. J. Hamoen, M. Staal, R. Sclabassi, R. Haaxma, A. Elands, J.J.J. Hummel
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Abstract

The objective of this work was to design and use a tremor recording and analysis system for stereotactic thalamotomy and thalamus stimulation (DBS). A notebook PC based system was developed. The tremor was measured by accelero-transducers or EMG. The method was used to confirm the definitive localization of the coagulation or stimulation target. Intra-operatively recorded effects of stimulation on the tremor were reproducible. Thermocoagulation and electrode implantation were done only after a significant reduction of the tremor was recorded on thalamic stimulation between 75 and 125 Hz. This method has been used on 9 patients: 2 underwent DBS implantation. It is concluded that intra-operative monitoring of the tremor during ventrolateral thalamotomy or stimulation is useful for identifying the final target for coagulation or electrode implantation.
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震颤记录和分析作为丘脑切开术和DBS治疗震颤的目标定位工具
本研究的目的是设计并使用立体定向丘脑切开术和丘脑刺激(DBS)的震颤记录和分析系统。开发了一个基于笔记本电脑的系统。震动是通过加速度传感器或肌电图测量的。该方法用于确定凝固或刺激目标的明确定位。术中记录的刺激对震颤的影响是可重复的。只有在75 - 125赫兹的丘脑刺激记录到震颤显著减少后,才进行热凝和电极植入。该方法已应用于9例患者,其中2例行DBS植入。结论术中监测腹外侧丘脑切开或刺激时的震颤有助于确定凝血或电极植入的最终目标。
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