Determination of aflatoxin B1 in cosmetics containing botanical ingredients by enzyme linked immunosorbent assay

I. Gazioğlu
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Abstract

DOI : 10.26650/IstanbulJPharm.2019.19017 Botanicals are widely used in cosmetic products due to their rich chemical compositions. There are numerous factors that affect the chemical profile of botanical content including growing, harvesting, drying and storage conditions. The reliability of a cosmetic product containing botanical ingredients is closely related to the quality control processes of the raw material. Aflatoxins can be transmitted to the botanicals at every stage of the production. The purpose of this study is to evaluate the ELISA method for the determination of aflatoxins in 20 personal care products containing plant extracts and/or oil. In this study, aflatoxin B1 (AFB1) was not detected in one of the samples containing chamomile extract, rose, shea & orange, and cocoa butter.  Of the tested samples, 35% exceeded the legal limits of AFB1. The highest level was determined in sample containing coconut butter (15.13 ppb). These results show that raw materials of cosmetic products should be regularly and effectively controlled.   Cite this article as : Gazioglu I (2019). Determination of aflatoxin B1 in cosmetics containing botanical ingredients by enzyme linked immunosorbent assay. Istanbul J Pharm 49 (2): 88-91.
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酶联免疫吸附法测定含植物成分化妆品中的黄曲霉毒素B1
植物药因其丰富的化学成分而广泛应用于化妆品中。有许多因素影响植物成分的化学特征,包括生长、收获、干燥和储存条件。含有植物成分的化妆品的可靠性与原料的质量控制过程密切相关。黄曲霉毒素可以在生产的每个阶段传播到植物中。本研究的目的是评价ELISA法测定含有植物提取物和/或油的20种个人护理产品中黄曲霉毒素的含量。在本研究中,含有洋甘菊提取物、玫瑰、乳木果和橙、可可脂的样品中未检测到黄曲霉毒素B1 (AFB1)。在测试样本中,35%的AFB1超过法定限量。含有椰子油的样品中含量最高(15.13 ppb)。这些结果表明,化妆品的原料应定期和有效地控制。本文引文为:Gazioglu I(2019)。酶联免疫吸附法测定含植物成分化妆品中的黄曲霉毒素B1。中华医学杂志,49(2):88-91。
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