Microbiome and skin

I. Bakardzhiev, Zhenya Stoyanova
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Abstract

The human skin is a dynamic ecosystem inhabited by bacteria, mites, fungi and viruses. This set of microorganisms living on the skin and mucous membranes of the oropharynx, upper respiratory tract, conjunctiva, colon and lower urogenital tract, is called „normal flora“ (physiological, natural, autochronous, microbiome, microbiota) and is essential for skin physiology and immunity. The development of molecular methods to identify microorganisms has led to an emerging view of the resident skin bacteria as highly diverse and variable. An enhanced understanding of the skin microbiome is necessary to gain insight into microbial involvement in human skin disorders and to enable novel promicrobial and antimicrobial therapeutic approaches for their treatment.
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微生物群和皮肤
人体皮肤是一个动态的生态系统,由细菌、螨虫、真菌和病毒居住。这组微生物生活在口咽、上呼吸道、结膜、结肠和下泌尿生殖道的皮肤和粘膜上,被称为“正常菌群”(生理的、自然的、同步的、微生物组、微生物群),对皮肤生理和免疫至关重要。分子方法鉴定微生物的发展已经导致了一个新兴的观点,即常驻皮肤细菌是高度多样化和可变的。加强对皮肤微生物组的了解对于深入了解微生物与人类皮肤疾病的关系以及为其治疗提供新的益生菌和抗菌治疗方法是必要的。
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