Use of honey as a viscosity modifier in the formulation of cotrimoxazole suspension

Abstract

A study has been carried out on honey from comb of bee, Apis mellifera .  L. (Family, Apidae) as a viscosity modifier in conjunction with certain suspending agents in the formulation of cotrimoxazole suspension, to solve the problem of caking associated with most brands in the market. Six formulations including control, with or without suspending agents were compared to commercial brands by determining sedimentation volume, flow rate and rheological properties of all the preparations. The results show that two out of five commercial brands had satisfactory suspendability characteristics (p Keywords: honey, suspending agent, viscosity modifier, suspension, cotrimoxazole Journal of Pharmaceutical and Allied Sciences , Vol. 7 No. 1 (2010)