{"title":"Intolerance to Aspirin: Clinical and Immunological Studies","authors":"G. Patriarca , A. Venuti , D. Schiavino , G. Fais","doi":"10.1016/S0300-872X(76)80024-8","DOIUrl":null,"url":null,"abstract":"<div><p>Skin-tests, patch-tests, Prausnitz-Küstner reactions, passive cutaneous anaphylaxis in guinea pigs according to Ovary and lymphocyte proliferation tests <em>in vitro</em> using thymidine 2-C<sup>14</sup> have been carried out in 31 patients with aspirin intolerance. Acetylsalicylic acid, aspiryl-polylysine, lysine acetylsalicylate, and sodium salicylate were used as antigens in these investigations. Collageninduced platelet aggregation according to BORN in the presence of aspirin was also studied.</p><p>An immunological mechanism was revealed in only a small percentage of the patients studied, indicating in the remaining cases the possible role of nonimmunological processes or the inadequacy of the test techniques employed.</p></div>","PeriodicalId":101289,"journal":{"name":"Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie","volume":"151 4","pages":"Pages 295-304"},"PeriodicalIF":0.0000,"publicationDate":"1976-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0300-872X(76)80024-8","citationCount":"11","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0300872X76800248","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 11
Abstract
Skin-tests, patch-tests, Prausnitz-Küstner reactions, passive cutaneous anaphylaxis in guinea pigs according to Ovary and lymphocyte proliferation tests in vitro using thymidine 2-C14 have been carried out in 31 patients with aspirin intolerance. Acetylsalicylic acid, aspiryl-polylysine, lysine acetylsalicylate, and sodium salicylate were used as antigens in these investigations. Collageninduced platelet aggregation according to BORN in the presence of aspirin was also studied.
An immunological mechanism was revealed in only a small percentage of the patients studied, indicating in the remaining cases the possible role of nonimmunological processes or the inadequacy of the test techniques employed.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
