Solubility: An overview

A. Singh, N. Singh, A. Singh
{"title":"Solubility: An overview","authors":"A. Singh, N. Singh, A. Singh","doi":"10.18231/J.IJPCA.2020.027","DOIUrl":null,"url":null,"abstract":"Solubility is a process of solute in solvent to give a homogenous framework which is the significant considerations to accomplish wanted concentration of drug in the systemic circulation for wanted pharmacological reaction. The bioavailability issue can be because of inadequate Solubility of permeability. Most mixes solutions are facing the solubility issues. Subsequently, with the progression of synthetic science, the need for improvement of drug innovations is likewise expanding. The mechanisms solute\nsolvent interaction expresses homogeneous liquid phases comprising of solute and solvent in factor proportions. The choice of solubility improving strategy relies upon drug property, site of retention, and required measurement structure attribute.\n\nKeywords: Solubility, Solubility expressions, BCS classification, Factors, Mechanisms, Biological principle.","PeriodicalId":13889,"journal":{"name":"International Journal of Pharmaceutical Chemistry and Analysis","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Pharmaceutical Chemistry and Analysis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18231/J.IJPCA.2020.027","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

Abstract

Solubility is a process of solute in solvent to give a homogenous framework which is the significant considerations to accomplish wanted concentration of drug in the systemic circulation for wanted pharmacological reaction. The bioavailability issue can be because of inadequate Solubility of permeability. Most mixes solutions are facing the solubility issues. Subsequently, with the progression of synthetic science, the need for improvement of drug innovations is likewise expanding. The mechanisms solute solvent interaction expresses homogeneous liquid phases comprising of solute and solvent in factor proportions. The choice of solubility improving strategy relies upon drug property, site of retention, and required measurement structure attribute. Keywords: Solubility, Solubility expressions, BCS classification, Factors, Mechanisms, Biological principle.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
溶解度:概述
溶解度是溶质在溶剂中形成均匀框架的过程,是实现药物在体循环中所需浓度以达到所需药理反应的重要考虑因素。生物利用度问题可能是由于渗透性溶解度不足。大多数混合溶液都面临溶解度问题。随后,随着合成科学的发展,对改进药物创新的需求也在扩大。溶质-溶剂相互作用机理表现为溶质和溶剂按因子比例组成的均匀液相。提高溶解度策略的选择取决于药物性质、保留部位和所需的测量结构属性。关键词:溶解度,溶解度表达式,BCS分类,因素,机制,生物学原理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Analytical method development and validation of UV-visible spectrophotometric method for the estimation of CNS stimulant drug in bulk Navigating pharmaceutical product decisions: A comprehensive review Preparation and evaluation of herbal sunscreen creams The regulatory quest for specific drugs marketed in India and western world-perception difference An overview: Herbal cosmetics and cosmeceuticals
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1