Lipid Profile of Obese Albino Rat after Treatment with Diets from Developed Recipes Utilizing Local Dietary Fibre Foodstuffs in Enugu State, Nigeria

Abstract

The study investigated the lipid profile of obese adult albino wista rat after treatment with diets from developed recipes utilizing local dietary fibre foodstuffs in Enugu State, Nigeria. The study adopted research and development design carried-out in seven phases via determining the fiber content of the developed local foodstuffs using the AOAC standard, developing 9 recipes like casiavitas, herb rice, breadfruit and corn kernel, jack bean risotta, cowpea and maize twist, amarantus delicacy, nestroe, local fruit mix and whole wheat bread, purchasing of fifty (50) female adult albino wista rats from Veterinary Department of University of Nigeria Nsukka (UNN), Random sampling technique was adopted in the selection of 90 subjects (20 Nutritionists, 40 Home Economists, 10 Agriculturists, 6 Food Analyst, 14 Dieticians, and 4 Veterinary Doctors) in Enugu State. Conditioning the rat with normal rat chow for one week, inducement of obesity on the rats with condensed milk and sugar, division of the rats into 10 groups (one as control and nine as experimental) of 5 rats each based on body weight, and lastly taking Body Mass Index Measurements and Lipid Profile Recordings (BMILPR) of the rats before, during and after treatment with the diets. Data obtained was analyzed using mean and standard deviation. The study revealed that all the developed local fibre dishes which contributed significantly to weight loss and reduction in cholesterol and other lipid profiles of adult albino wista rats can be inferred in man. However, local fruit mix has the highest HDL and TGL reduction (from 40.97 after obesity inducement to 32.29 after treatment) and (from 97.83 to 25.81) respectively. The study recommends that local dietary fibre rich dishes should be used for women with obesity and lipid profile challenges.