A Review on Analytical Method for Determination of Venlafaxine HCl in Bulk and Pharmaceutical dosage form

Swamini A Dighe, S. Siddheshwar, G. Shinde
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Abstract

Venlafaxine HCl is one of the antidepressant agent which comes under the category of serotonin-norepinephrine reuptake inhibitor i.e SNRI. This medication is usually used to treat major depressive disorder in adult. It may help to improve the mood and energy level and also to regain the interest in daily activities in the depressed person. The present review focus on various approaches for the analysis on Venlafaxine in bulk and pharmaceutical dosage forms. The review represents the various analytical method like the RP-HPLC, HPTLC, UV Spectroscopy and Stability Indicating Methods which were used for the investigation of Venlafaxine in bulk and different dosage formulations.
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盐酸文拉法辛原料药和制剂剂型分析方法综述
文拉法辛是一种抗抑郁药,属于5 -羟色胺-去甲肾上腺素再摄取抑制剂(SNRI)的范畴。该药通常用于治疗成人重度抑郁症。它可能有助于改善抑郁症患者的情绪和能量水平,并重新获得对日常活动的兴趣。本文综述了文拉法辛原料药和制剂剂型的各种分析方法。综述了文拉法辛原料药和不同剂量制剂的RP-HPLC、HPTLC、UV、稳定性指示等分析方法。
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