Kawasaki Disease Complicated by Peripheral Gangrene in a Case of Inherited Thrombophilia

Faten Al Tasseh, H. Khatib, Rodaina Kordab, S. Ghanem, Z. Naja, A. Naja, Georges Haber, M. Rajab, Malek J Baassiri, R. Haidar
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引用次数: 3

Abstract

Kawasaki disease is a febrile vasculitis targeting medium sized arteries, causing coronary artery aneurysm without appropriate treatment. Many children do not fulfill the criteria and due to its serious complications, the American Heart Association (AHA) published an algorithm for atypical Kawasaki disease based on laboratory tests and echocardiography. Peripheral ischemia is a rare complication with harmful sequalae. Here we reports a case of a 14-month-old patient, who was diagnosed of atypical Kawasaki disease, developed peripheral ischemia and gangrene of the second and third right hand fingers, and was found to have factor V Leiden heterozygous mutation. Int J Clin Pediatr. 2018;7(3):43-45 doi: https://doi.org/10.14740/ijcp306w
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川崎病并发外周坏疽一例遗传性血栓病
川崎病是一种以中等动脉为目标的发热性血管炎,未经适当治疗可引起冠状动脉瘤。许多儿童不符合标准,由于其严重的并发症,美国心脏协会(AHA)发布了一种基于实验室检查和超声心动图的非典型川崎病算法。外周缺血是一种罕见的并发症,并伴有有害的后遗症。我们报告一例14个月大的患者,诊断为不典型川崎病,发生外周缺血和坏疽的右手第二和第三指,发现有因子V Leiden杂合突变。国际儿科临床杂志,2018;7(3):43-45 doi: https://doi.org/10.14740/ijcp306w
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