Olfactory Dysfunction in Covid-19 Patients, The Current Evidence and Literature Review

Ali Almomen
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Abstract

Background: Osteoma, fibrous, dysplasia and ossifying fibroma are fibro-osseus lesions that can occur in the paranasal sinuses, management of these lesions can be technically challenging due to proximity to the orbit and skull base, with the advancement in endoscopic endonasal surgery and development of technologies such as image guidance can improve the safety of endoscopic removal and improve its safety. Illustrative cases : Three cases of fibro-ossuoes lesions are presented in this study an adult female with left frontoethmoidal osteoma, an adult male with left ethmoid fibrous dysplasia, both of whom have been treated with pure endonasal endoscopic approach with image guidance, the third case is a male child with juvenile ossifying fibroma, he was treated initially with the endoscopic approach with image guidance, but had a skull base recurrence 6 months later which was removed with an open craniotomy approach. Conclusion: Image guidance is a valuable tool in improving safety and efficiency of endoscopic sinus surgery particularly in challenging cases such as fibro-osseus lesions with proximity to the skull base and orbit.
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Covid-19患者的嗅觉功能障碍,当前证据和文献综述
背景:骨瘤、纤维性纤维瘤、发育不良纤维瘤和骨化性纤维瘤是可发生在鼻窦炎的纤维-骨性病变,由于靠近眼眶和颅底,这些病变的治疗在技术上具有挑战性,随着鼻内窥镜手术的进步和图像引导等技术的发展,可以提高内镜切除的安全性,提高其安全性。说明性案例:本研究报告3例纤维-骨骨病变,1例成年女性左侧额筛骨瘤,1例成年男性左侧筛纤维发育不良,均采用单纯内镜下图像引导入路治疗,第三例为男童幼年骨化纤维瘤,最初采用内镜下图像引导入路治疗,6个月后颅底复发,开颅手术切除。结论:图像引导是提高鼻窦内窥镜手术安全性和效率的重要工具,特别是在接近颅底和眼眶的纤维骨性病变等具有挑战性的病例中。
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