D. Felício, D. S. Pereira, A. M. Assumpção, F. Jesus-Moraleida, B. Z. Queiroz, J. P. Silva, Naysa Maciel de Brito Rosa, João M. D. Dias, L. Pereira
{"title":"Systemic inflammation and physical function in community elderly women","authors":"D. Felício, D. S. Pereira, A. M. Assumpção, F. Jesus-Moraleida, B. Z. Queiroz, J. P. Silva, Naysa Maciel de Brito Rosa, João M. D. Dias, L. Pereira","doi":"10.14800/ICS.368","DOIUrl":null,"url":null,"abstract":"Multiple inter-related factors that contribute to the development and progression of sarcopenia in the elderly. Sarcopenia is enhanced by immunosenescence, in which the induction and expression of inflammatory mediators such as IL-6 and TNF-α increase significantly. High levels of plasma cytokines are a predictor of mortality and morbidly in the elderly and have a catabolic effect on muscle proteins. Our studies show that there is no a cutoff point to predict adverse physical and functional outcomes, the data found are conflicting. More research is needed to clarify the role of systemic inflammation in muscle and functional performance in elderly women.","PeriodicalId":13679,"journal":{"name":"Inflammation and cell signaling","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2014-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Inflammation and cell signaling","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14800/ICS.368","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Multiple inter-related factors that contribute to the development and progression of sarcopenia in the elderly. Sarcopenia is enhanced by immunosenescence, in which the induction and expression of inflammatory mediators such as IL-6 and TNF-α increase significantly. High levels of plasma cytokines are a predictor of mortality and morbidly in the elderly and have a catabolic effect on muscle proteins. Our studies show that there is no a cutoff point to predict adverse physical and functional outcomes, the data found are conflicting. More research is needed to clarify the role of systemic inflammation in muscle and functional performance in elderly women.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
