Acute necrotizing eosinophilic myocarditis successfully treated by high dose methylprednisolone.

Nozomi Watanabe, Susumu Nakagawa, Takashi Fukunaga, Shuji Fukuoka, Kinta Hatakeyama, Tohru Hayashi
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引用次数: 42

Abstract

Acute necrotizing eosinophilic myocarditis is the most severe form of eosinophilic myocarditis, or hypersensitivity myocarditis, and is characterized by rapidly progressive congestive heart failure followed by fulminant clinical deterioration that is nearly always fatal. A 55-year-old previously healthy patient with acute necrotizing eosinophilic myocarditis was diagnosed by early myocardial biopsy and successfully treated with corticosteroids. Throughout his hospitalization, the eosinophil count in the peripheral blood remained normal (56-201/mm3). Early stage corticosteroid therapy can have dramatic effects in acute necrotizing eosinophilic myocarditis and early diagnosis by endomyocardial biopsy is recommended.
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大剂量甲基强的松龙治疗急性坏死性嗜酸性心肌炎成功。
急性坏死性嗜酸性心肌炎是嗜酸性心肌炎或超敏性心肌炎的最严重形式,其特征是迅速进行性充血性心力衰竭,随后出现暴发性临床恶化,几乎总是致命的。一例55岁健康的急性坏死性嗜酸性心肌炎患者通过早期心肌活检诊断并成功使用皮质类固醇治疗。在住院期间,外周血嗜酸性粒细胞计数保持正常(56-201/mm3)。早期皮质类固醇治疗对急性坏死性嗜酸性心肌炎有显著效果,建议通过心内膜活检进行早期诊断。
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