Sociodemographic Characteristics and Clinical Presentation of Infertile Women with Polycystic Ovary Syndrome in a Tertiary Care Hospital

Abstract

Background: Infertility has been an issue of concern especially for women for decades, and one of the identified etiological factors is polycystic ovary syndrome (PCOS) that impact on ovulation and conception. Aim: This study aims to study the sociodemographic characteristics and clinical presentationof infertile women with (POS). Materials and methods : In this prospective case-control study, out of 150 infertile patients 75 women served as PCOS group. The demographic details such as age, socioeconomic class, employment status residential area, Body mass index, menstrual patterns, clinical presentation, and infertility related lab values were noted.The collected data were statistically analyzed using the Chi-square test. Results: The prevalence of PCOS was high in the age group 24 to 27 years (37.33%), from middle socioeconomic class (45%), residing in urban areas (62.67%) and housewives (65.33%). Most of the PCOS patients were overweight (32%) and obese (21.33%) and showed statistical significance p = 0.021 and p = 0.021 respectively. Oligomenorrhea (54.67%) and amenorrhea (40%) were the commonly found clinical presentations. Weight gain (p = 0.000) and acne (p = 0.049) were found to be significant. Also, a significant relationship was seen for Luteinizing Hormone (LH) (p = 0.003) and Prolactin (p = 0.001) in both groups. Conclusion: In this study, the prevalence of PCOS was high in patients from a middle socio-economic class, residing in urban areas and obese patients. Oligomenorrhea was found to be the most common clinical presentation in PCOS patients. Furthermore, evidence of high LH and Prolactin levels were found that is known to be associated with hyperandrogenism in PCOS patients.