Karina E. Hew , Arvind Bakhru , Evan Harrison , Mehmet O. Turan , Ryan MacDonald , Dwight D. Im , Neil B. Rosenshein
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引用次数: 5
Abstract
Introduction/Background
The objective of this study was to examine whether obesity affects the time to recurrence in primary epithelial ovarian cancer.
Patients and Methods
A multicenter retrospective chart review was performed between 2004 and 2009. Three hundred seventy patients were eligible for analysis. Demographic and clinicopathological variables and treatment-related data were collected. Women with a body mass index (BMI) > 30 were categorized as obese. The time to recurrence was quantified in terms of months. Survival analyses were performed using the Kaplan-Meier method and compared using log-rank testing.
Results
One hundred thirty (35%) obese patients were compared with 240 (65%) nonobese patients. A recurrence was documented in 125 (47.9%) nonobese patients and 49 (37.7%) obese patients. Time to recurrence between both BMI groups was identical, at 15 months (P = 1.0). The progression-free survival was similar in obese and nonobese subjects (P = .118).
Conclusion
Obesity does not affect the recurrence time in patients with primary ovarian cancer.