Microneedles: A Pharmaceutical Review

Abstract

Microneedles (MNs) are one of the efficient and a unique technique of a drug delivery. MNs are a transdermal drug delivery system which is painless, less invasive with a high drug bioavailability. Over the several years, various research around the world have reported superb featuresof MNs in distinct areas of health care. In relation to the wise use of MNs, in this review we deal in depth with the types of MNs, present fabrication methods, and applications of MNs in drug delivery. Recent advancements in 3D printing and digital technology are contributing to the betterment of MNs fabrication technology. Transdermal drug delivery has the advantage of bypassing the first-pass effect as well as allows the sustained release of the drug. MNs are a transdermal drug delivery system that is painless, less invasive, and easy to self-administer, with a high drug bioavailability. The present review coversseveral fabricating materials and fabrication methods which are used for MN preparation. This review also covers the distinctive applications of MNs, which holds great potential in health care industry.