Real-Time Thermoacoustic Imaging and Thermometry during Focused Microwave Heating in Multilayer Breast Phantom

Chandra Karunakaran, Srishti Saraswat, J. Tak, Hongbo Zhao, H. Xin, R. Witte
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引用次数: 4

Abstract

This study describes real-time thermoacoustic imaging (TAI) and thermometry (TAT) for feedback during thermal therapies. The system uses a linear ultrasound array and imaging system to noninvasively estimate temperature. The system was validated in gel phantoms, muscle and fat tissue samples. A mean error between 10 and 20% per degree was observed for estimating temperature. A TAT system using a single element ultrasound probe was also integrated with a focused microwave therapy (FMT) setup for generating local heating, leading to a mean error of 1.18±0.87 °C compared to thermocouples placed near the region of interest. The results support the long-term goal of developing a closed-loop platform for image-guided ablation therapy for breast cancer.
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多层乳房幻影聚焦微波加热过程中的实时热声成像和测温
本研究描述了实时热声成像(TAI)和测温(TAT)在热治疗过程中的反馈。该系统使用线性超声阵列和成像系统来无创地估计温度。该系统在凝胶模型、肌肉和脂肪组织样本中得到了验证。估计温度的平均误差在每度10%到20%之间。使用单元件超声探头的TAT系统还集成了聚焦微波治疗(FMT)装置,用于产生局部加热,与放置在感兴趣区域附近的热电偶相比,平均误差为1.18±0.87°C。该结果支持开发一个用于乳腺癌图像引导消融治疗的闭环平台的长期目标。
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