Presence of Aflatoxin Carcinogens in Fresh and Mature Cheeses

Rojas-Marín, M. Carvajal-Moreno, González-Villaseñor Mc, García-Hernández Ea, A. González-Mendoza
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引用次数: 7

Abstract

Cheese has a high nutritional value so it is considered an essential food in the human diet. This review considered 27 countries with 59 different kinds of cheeses highly consumed per person, with France and the USA as the largest consumers with 26 kg and 15 kg per inhabitant per year, respectively. Mexico has a consumption of 2.1 kg per capita in a year. The presence of aflatoxins in cheeses represents a risk for human health because the International Agency for the Research of Cancer (IARC) classified them as Grade I, meaning that they are proven carcinogens to humans. Almost all of the countries reported aflatoxin M1 in cheese, and only Mexico analyzed eight different aflatoxins and hydroxylates in this dairy product. It is also important to analyze the hydroxylate metabolites of aflatoxins because they are also carcinogenic and they increase the amount of ingested carcinogens in cheese samples, allowing us to obtain the real ingested dose.
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新鲜和成熟奶酪中黄曲霉毒素致癌物的存在
奶酪具有很高的营养价值,因此它被认为是人类饮食中必不可少的食物。这项审查考虑了27个国家,人均消费59种不同的奶酪,其中法国和美国是最大的消费者,每人每年分别消费26公斤和15公斤奶酪。墨西哥的人均年消费量为2.1公斤。奶酪中黄曲霉毒素的存在对人类健康构成威胁,因为国际癌症研究机构(IARC)将其列为一级,这意味着它们已被证明是对人类的致癌物。几乎所有的国家都报告了奶酪中的黄曲霉毒素M1,只有墨西哥分析了这种乳制品中的八种不同的黄曲霉毒素和羟基酸盐。分析黄曲霉毒素的羟基化代谢物也很重要因为它们也具有致癌性它们会增加奶酪样品中摄入的致癌物的量,从而使我们能够获得真正的摄入剂量。
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