Determination of Quinolones in Human Urine and Water Samples by Ultrasound Assisted Dispersive Liquid-Liquid Microextraction Based on Solidification of Floating Organic Droplet Followed High Performance Liquid Chromatography

Sen Lv, Yiqing Sun, Ying-lai Yang, Z. Niu, Yingying Wen
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Abstract

Quinolones (QNs) are the most important class of synthetic antibiotics in human and veterinary medicines. They are effective to control a wide range of bacteria, both gram positive and negative as well as other bacteria and often used in the treatment of a range of illnesses. Due to the fact that its resistance in the environment can cause undesirable effects on aquatic ecosystems and human health, QNs have obtained growing attention [1,2]. Therefore, the analysis of the occurrence, distribution and risks of quinolone antibiotics became crucial to environment monitoring.
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超声辅助分散液-液微萃取-高效液相色谱法测定人体尿液和水样中的喹诺酮类药物
喹诺酮类药物是人类和兽药中最重要的一类合成抗生素。它们能有效控制多种细菌,包括革兰氏阳性和阴性细菌以及其他细菌,经常用于治疗一系列疾病。由于其在环境中的抗性会对水生生态系统和人类健康造成不良影响,QNs受到越来越多的关注[1,2]。因此,分析喹诺酮类抗生素的发生、分布及风险对环境监测至关重要。
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