Utilidad de los marcadores bioquímicos de preeclampsia

M.a José Alcaine Villarroya , Eva M. Barrenechea Iparraguirre , Elena Casals , Concepción González Rodríguez , Inmaculada Martín Navas , Hada Macher Manzano , M. Concepción Martínez Camarasa , Daniel Morell García , Helena Méndez Sol , Irene Rosas Allende , Elvira Tejedor Hernández , Belén Prieto García
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Abstract

Pre-eclampsia (PE) is one of the leading causes of maternal and perinatal mortality in the world. In developed countries, studies point to a significant increase in the incidence of PE in the last decade, partly due to the increase in the prevalence in the general population of diseases that affect vascular function, such as diabetes. chronic hypertension, or kidney disease. An updated review of PE is presented in this article. The diagnostic criteria and the pathophysiology of the disease are described. The main objective of the document is to review the new biochemical markers that may be useful in clinical practice for the prediction and diagnosis of PE, as well as the different methods by which yey can be determined.

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子痫前期生化标志物的应用
先兆子痫(PE)是世界上孕产妇和围产期死亡的主要原因之一。在发达国家,研究指出,在过去十年中,PE的发病率显著增加,部分原因是影响血管功能的疾病(如糖尿病)在普通人群中的患病率增加。慢性高血压或肾脏疾病。本文介绍了PE的最新综述。介绍了本病的诊断标准和病理生理。本文的主要目的是综述可能在临床实践中对PE的预测和诊断有用的新的生化标志物,以及可以确定PE的不同方法。
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