Comparison of self-rated pain and salivary alpha-amylase and cortisol levels during early stages of fixed orthodontic and clear aligner therapy.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-11-01 Epub Date: 2023-07-19 DOI:10.1080/00016357.2023.2236214

Dena Ali, Hassan Abdal, Mubarak Alsaeed

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引用次数: 0

Abstract

Objectives: To compare self-rated orthodontic pain (OP) and whole salivary alpha-amylase (αA) and cortisol levels (CL) during early stages of fixed orthodontic and clear aligner therapy (CAT).

Methods: In groups 1 and 2, malocclusions were treated using fixed orthodontic appliances and CAT, respectively. In Group-3, individuals had normal occlusion and had never undergone orthodontic therapy. Self-rated OP was assessed using the visual-analogue-scale at baseline (T0); after 24-hours (T1) of appliance activation; and after 30 days (T2). Unstimulated whole saliva was collected and αA and CL were measured using enzyme-linked immunosorbent assay. p < .01 was considered statistically significant.

Results: Twenty-four (Group-1), 24(Group-2) and 25 (Group-3) patients were included. In groups 1 and 2, participants had Class-I malocclusion with anterior-crowding in both arches. At baseline (T0) none of the participants reported pain on mastication. In groups 1 (p < .01) and 2 (p < .01), OP was higher at T1 than T2. In groups 1 and 2, αA and CL were higher at T1 (p < .01) than T0 and T2. At T1 and T2, salivary αA and CL were higher in groups 1 (p < .01) and 2 (p < .01) than Group-3. In groups 1 and 2, a significant correlation was recorded between OP and αA (p < .01) and CL (p < .01) at T1 interval.

Conclusion: Self-rated OP and salivary αA and CL during the early stages of fixed OT and CAT are similar. Whole salivary αA and CL and OP and are high during the first 24 hours of fixed OT and CAT activation.

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固定正畸和透明矫正器治疗早期阶段的自评疼痛、唾液α-淀粉酶和皮质醇水平的比较。

目的：比较固定正畸和透明矫正器治疗（CAT）早期的自评正畸疼痛（OP）、全唾液α-淀粉酶（αA）和皮质醇水平（CL）。在第3组中，个体咬合正常，从未接受过正畸治疗。自评OP在基线（T0）时使用视觉模拟量表进行评估；在器具激活24小时（T1）之后；30岁以后天（T2）。收集未刺激的全唾液，用酶联免疫吸附法测定αA和CL。p 结果：包括24例（第一组）、24例（第二组）和25例（第三组）患者。在第1组和第2组中，受试者均患有I类错牙合，两个足弓均出现前方拥挤。在基线（T0），没有一名参与者报告咀嚼疼痛。在第1组（p p p p p p p 结论：固定OT和CAT早期的自评OP与唾液αA和CL相似。整个唾液αA、CL和OP在前24小时内都很高固定OT和CAT激活的小时数。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.