Hypomagnesemia because of nedaplatin for cervical cancer: A case report

IF 1.8 Q2 MEDICINE, GENERAL & INTERNAL Journal of General and Family Medicine Pub Date : 2023-06-02 DOI:10.1002/jgf2.630
Jun Komoda MD, Tetsuya Hori MD, Kotaro Sato MD, PhD, MPH, Kunio Kusajima MD, Taro Shimizu MD, PhD, MPH, MBA
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Abstract

A 76-year-old woman with cervical cancer was treated with nedaplatin, a platinum-based drug. After the initiation of the treatment, she became aware of numbness, dizziness, and loss of appetite. Exploration of the causes revealed no clues, but blood tests revealed hypocalcemia and hypomagnesemia. She was treated with intravenous calcium and magnesium, which resolved calcium, magnesium levels, and her symptoms. She was diagnosed with hypomagnesemia because of nedaplatin. Regular follow-up is necessary for patients during or after nedaplatin. Awareness of electrolyte disturbances may elucidate the accurate diagnosis even in patients with obscure symptoms, particular in undergoing or following anticancer therapies.

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奈达铂治疗宫颈癌致低镁血症1例
一名76岁的宫颈癌妇女接受了奈达铂治疗,这是一种以铂为基础的药物。开始治疗后,她感到麻木、头晕、食欲不振。对病因的调查没有发现任何线索,但血液检查显示低钙血症和低镁血症。她接受静脉钙镁治疗,钙镁水平得到缓解,症状得到缓解。由于服用奈达铂,她被诊断为低镁血症。在奈达铂治疗期间或之后,患者需要定期随访。意识到电解质紊乱可以阐明准确的诊断,甚至在症状不明确的患者,特别是在接受或随后的抗癌治疗。
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来源期刊
Journal of General and Family Medicine
Journal of General and Family Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
2.10
自引率
6.20%
发文量
79
审稿时长
48 weeks
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