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The Effect of Chrysin Nanoparticles in Preventing the Growth of Mcf-7 Cancer Cells 白菊花素纳米颗粒对Mcf-7癌细胞生长的抑制作用
Q4 Medicine Pub Date : 2018-10-10 DOI: 10.18869/ACADPUB.JBUMS.20.10.56
M. Norouzi, Sl Rezazadeh, A. Moghadamnia, N. Bahramifar, L. Barari, S. Kazemi
1.Department of Chemistry, Payame Noor University, Tehran, I.R.Iran 2.Student Research Committee, Babol University of Medical Science, Babol, I.R.Iran. 3.Cellular and Molecular Biology Research Center, Health Research Center, Babol University of Medical Sciences, Babol, I.R.Iran 4.Department of Environmental Science, Faculty of Natural Resources and Marine Sciences, Tarbiat Modares University, Noor, I.R.Iran 5.Neuroscience Research Center, Health Research Institute, Babol University of Sciences, Babol, I.R.Iran
1.帕亚姆努尔大学化学系,德黑兰,伊朗巴博勒医学院学生研究委员会,巴博勒,伊朗。3.巴博勒医科大学健康研究中心细胞与分子生物学研究中心,巴博勒,伊朗塔尔比亚尔莫达雷斯大学自然资源与海洋科学学院环境科学系,伊朗努尔巴博勒科学大学健康研究所神经科学研究中心,巴博勒,伊朗
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引用次数: 1
Association the study of between CPEB1 (rs230846 C>T) gene polymorphism and azoospermia/ severe oligospermia CPEB1 (rs230846 C>T)基因多态性与无精子症/严重少精子症的相关性研究
Q4 Medicine Pub Date : 2018-09-10 DOI: 10.18869/ACADPUB.JBUMS.20.9.20
S. Ghorbian, R. Bostanabad
BACKGROUND AND OBJECTIVE: : CPEB1 gene plays a significant role during gametogenesis. Due to remain unclear many causes of male infertility, we aimed to evaluate the association between of CPEB1 rs2303846 gene polymorphism with the risk of men with idiopathic azoospermia/ severe oligospermia. METHODS: The present study is a case-control investigation, were performed on 100 peripheral blood samples of men with idiopathic azoospermia/ severe oligozoospermia and 100 blood samples of healthy men, who were referred to department of infertility and sterility of Tabriz Al-Zahra hospital from 2015 to 2017. The PCR-RFLP method was used to determine the frequency of genotypes and then compared the relationship between polymorphism and clinical parameters. FINDINGS: The genotypes frequency of CEBP1 gene polymorphism CT+TT/CC did not show a statistically significant difference between groups (P=0.395, OR=1.273; CI=0.730-2.220). In addition, no significant correlation was found between genotypes and FSC, MSC and SMI clinical parameters (p<0.05). CONCLUSION: Findings revealed that CEBP1 rs2303846 gene polymorphism cannot to be considered as a risk factor for idiopathic azoospermia/ severe oligospermia men.
背景与目的:CPEB1基因在配子发生过程中起重要作用。由于男性不育的许多原因尚不清楚,我们旨在评估CPEB1 rs2303846基因多态性与男性特发性无精子症/严重少精子症风险之间的关系。方法:本研究采用病例对照调查方法,对2015 - 2017年在大不里士扎赫拉医院不孕不育科转诊的100例特发性无精子症/严重少精子症男性患者外周血和100例健康男性血液样本进行分析。采用PCR-RFLP法测定基因型频率,比较多态性与临床参数的关系。结果:CEBP1基因多态性CT+TT/CC基因型频率组间差异无统计学意义(P=0.395, OR=1.273;CI = 0.730 - -2.220)。基因型与FSC、MSC、SMI临床参数无显著相关性(p<0.05)。结论:CEBP1 rs2303846基因多态性不能作为男性特发性无精子症/严重少精子症的危险因素。
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引用次数: 0
Prevalence of Amblyopia in Iranian Children 伊朗儿童弱视的患病率
Q4 Medicine Pub Date : 2018-09-10 DOI: 10.18869/ACADPUB.JBUMS.20.9.72
M. Mohammadi, AA Vaisi Raiegan, R. Jalali, S. Salimpour, Akram Ghobadi, Parvin Abbasi
J Babol Univ Med Sci; 20(9); Sep 2018; PP: 72-9 Received: Apr 9 2018, Revised: Jul 28 2018, Accepted: Aug 1 2018. ABSTRACT BACKGROUND AND OBJECTIVE: Amblyopia is one of the common eye diseases in children and the risk of vision loss is possible. Therefore, the aim of this study is systematic review and meta-analysis in order to align the studies on the prevalence of amblyopia in Iranian children. METHODS: In this systematic review and meta-analysis relevant articles in scientific databases including SID, Science Direct and Medline (PubMed) and Google Scholar in March 1999February 2017, using the Persian and English
巴宝勒大学医学杂志;20 (9);2018年9月;收稿日期:2018年4月9日,修稿日期:2018年7月28日,收稿日期:2018年8月1日。背景与目的:弱视是儿童常见眼病之一,存在视力丧失的危险。因此,本研究的目的是系统回顾和荟萃分析,以协调有关伊朗儿童弱视患病率的研究。方法:本研究对1999年3月至2017年2月在SID、Science Direct、Medline (PubMed)和Google Scholar等科学数据库中使用波斯语和英语检索的相关文章进行系统综述和meta分析
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引用次数: 0
Effect of Facilitated Tucking with the Nurse and a Simulated Hand on Physiological Pain Index During Vein Puncture on Premature Infants 护士辅助收纳与模拟手对早产儿静脉穿刺生理疼痛指数的影响
Q4 Medicine Pub Date : 2018-09-10 DOI: 10.18869/ACADPUB.JBUMS.20.9.14
N. Salmani, Z. Karjo, Kh Dhghani, A. Sadeghnia
BACKGROUND AND OBJECTIVE: Painful and stressful stimuli increase catecholamine, heart rate, blood pressure and increase the intracranial pressure of the baby. Facilitated tucking is a simple technique that makes the baby control her body better. Therefore, this study was performed to compare the effects of fetal status with hands of nurses and simulated hand on the physiological indices of pain during venipuncture in preterm infants. METHODS: The present experimental study was performed on 99 preterm infants admitted to the intensive care unit of Amin and Shahid Beheshti hospitals of Isfahan and in three groups of 33 patients (two groups of test and one control group). In one of the test groups during venipuncture procedure neonates were placed in facilitated tucking by nurse’s hand and in the other group by simulated hands. Before, during and after the intravenous route, the respiratory rate, pulse rate and arterial oxygen saturation were recorded using monitors. FINDINGS: The mean of arterial oxygen saturation during and after venipuncture in the nurses' hand group were (93.04±6.13) and (94.3±56.44) and in simulated hand group were (95.2±21.11) and (94.2±50.86%) which had no significant difference (p<0.05). Between the mean respiratory rate, during and after the venipuncture in the nurses' hand (49.9±85.88) and (54.11±03.85) with simulated hand group (50.64±11.48) and (57.10±96.82) was not significantly
背景与目的:疼痛和压力刺激会增加儿茶酚胺、心率、血压和婴儿颅内压。方便掖被子是一种简单的技巧,可以让宝宝更好地控制自己的身体。因此,本研究比较了胎儿状态下护士手和模拟手对早产儿静脉穿刺疼痛生理指标的影响。方法:选取伊斯法罕市Amin和Shahid Beheshti医院重症监护室收治的99例早产儿为研究对象,分为三组,每组33例(两组为试验组,一组为对照组)。在静脉穿刺过程中,其中一组新生儿被护士的手放在方便的收纳处,另一组被模拟的手放在收纳处。静脉给药前、中、后分别用监护仪记录呼吸频率、脉搏率和动脉血氧饱和度。结果:护理手组静脉穿刺前后动脉血氧饱和度平均值分别为(93.04±6.13)和(94.3±56.44),模拟手组分别为(95.2±21.11)和(94.2±50.86%),差异无统计学意义(p<0.05)。护士手部静脉穿刺前后平均呼吸频率(49.9±85.88)与模拟手组(50.64±11.48)、(57.10±96.82)比较,差异无统计学意义
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引用次数: 3
مقایسه اثر مصرف کوتاه مدت کیک پروبیوتیک (باسیلوس کواگولانس) با کیک معمولی بر شمارش استرپتوکوک موتانس بزاق
Q4 Medicine Pub Date : 2018-09-10 DOI: 10.18869/ACADPUB.JBUMS.20.9.48
مریم کوپایی, ثنا جهانگیر, روناک بختیاری
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引用次数: 0
The Modulatory Effects of Aqueous Extract of the Plant Biebersteinia Multifida on the Gastric Acid Level and Intestinal Cytokines in Ulcerative Colitis Model 多假连翘水提物对溃疡性结肠炎模型胃酸水平和肠道细胞因子的调节作用
Q4 Medicine Pub Date : 2018-09-10 DOI: 10.18869/ACADPUB.JBUMS.20.9.7
Z. Keshavarzi, M. Nazari, Z. Razmi, M. Behnamfar
BACKGROUND AND OBJECTIVE: Inflammatory bowel disease is a chronic disease of the gastrointestinal tract with unknown etiology, which includes crohn's disease and ulcerative colitis (UC). Because an effective treatment has not been found so far, the present study was designed to investigate the effects of aqueous extracts of Biebersteinia multifida plant on inflammatory changes of the colon following acetic acidinduced ulcerative colitis in male rats. METHODS: In this experimental study, 32 male wistar rats weighing 200-250 g were used in vivo. Animals were randomly assigned into four groups (each group consisting of 8 rats): 1Intact; 2Acetic acid-induced ulcerative colitis; 3Biebersteinia multifida aqueous extract (200 mg /Kg); 4Sulfasalazine treatment group (500 Mg /kg). In each group, the amount of gastric acid and intestinal TNF-α and IL-10 cytokines were measured at 8 days after of ulcerative colitis induction. FINDINGS: The concentration of gastric acid in the induction group of colitis was 2/4533 ± 0.95 mEq/15 min, which in the treatment group with Biebersteinia multifida extract decreased the level of gastric acid to 0.4400 ± 0.17 (p = 0.000). Also, TNF-α changes in the colitis and extract group were 279.68±42.71 and 160.35±28.79, respectively, which was significant (p=0.000). The concentration of IL-10 in the colitis group was 349.75±31.89, which increased to 353.75±66.46 after injection of the extract (p=0.015). CONCLUSION: The results showed that aqueous extract of Biebersteinia multifida in a dose of 200 mg/kg has an effect on colon inflammation and it can be improved.
背景与目的:炎症性肠病是一种病因不明的胃肠道慢性疾病,包括克罗恩病和溃疡性结肠炎(UC)。由于目前尚未发现有效的治疗方法,本研究旨在探讨多裂藤水提物对醋酸性溃疡性结肠炎雄性大鼠结肠炎症变化的影响。方法:采用雄性wistar大鼠32只,体重200 ~ 250 g。实验动物随机分为四组,每组8只大鼠:1完整;2醋酸致溃疡性结肠炎;3 .多假比伯斯坦水提物(200 mg /Kg);4柳氮磺胺嘧啶治疗组(500 Mg /kg)。在溃疡性结肠炎诱导后8 d,检测各组胃酸和肠道TNF-α、IL-10细胞因子的含量。结果:结肠炎诱导组胃酸浓度为2/4533±0.95 mEq/15 min,多假啤酒花提取物治疗组胃酸浓度降低至0.4400±0.17 (p = 0.000)。结肠炎组和提取物组TNF-α的变化分别为279.68±42.71和160.35±28.79,差异均有统计学意义(p=0.000)。结肠炎组IL-10浓度为349.75±31.89,注射提取物后升高至353.75±66.46 (p=0.015)。结论:多假比伯藤水提物在200 mg/kg剂量下对结肠炎症有一定的改善作用。
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引用次数: 3
Effect of Motor Imagery Training with Sensory Feedback on Sensory-Motor Function of the Upper Extremity in Patients with Chronic Stroke 感觉反馈运动想象训练对慢性脑卒中患者上肢感觉-运动功能的影响
Q4 Medicine Pub Date : 2018-09-10 DOI: 10.18869/ACADPUB.JBUMS.20.9.28
A. Azad, A. Mahmodi, Z. Arani-Kashani
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引用次数: 3
The Effect of Aromatherapy with Peppermint Essential Oil on Nausea and Vomiting in the Acute Phase of Chemotherapy inPatients with Breast Cancer 薄荷精油芳香疗法对乳腺癌化疗急性期恶心呕吐的影响
Q4 Medicine Pub Date : 2018-09-10 DOI: 10.18869/ACADPUB.JBUMS.20.9.66
M. Eghbali, S. Varaei, M. Hosseini, M. Yekaninejad, F. Shahi
BACKGROUND AND OBJECTIVE: Chemotherapy is one of the main treatment options for cancer patients. Nausea and vomiting are also the most common side effects of chemotherapy drugs. The aim of this study was to determine the effect of aromatherapy with peppermint essential oil on nausea and vomiting in the acute phase of chemotherapy (the first 24 hours) in patients with breast cancer. METHODS: This randomized clinical trial was conducted on 100 women with breast cancer who were referred to the chemotherapy centers of Imam Khomeini Hospital on an outpatient basis for the first course. Patients were randomly divided into intervention and control groups. Peppermint essential oil was used in the intervention group, while normal saline was used in the control group. Frequency and severity of acute nausea and vomiting in the first night after chemotherapy were recorded and compared using Rhodes standard questionnaire with a mean score of 0 – 32. FINDINGS: The two groups were not statistically different in terms of age, duration of cancer, history of alcohol abuse and history of nausea and vomiting. The mean score of nausea in the aromatherapy group was 1.1±1.02 and in the in the control group was 1.82±1.39 (p<0.014). The mean score of vomiting in the intervention group was 0.34±0.66 and in the control group was 0.66±0.97 (p<0.032). CONCLUSION: The results of this study showed that the use of aromatherapy with peppermint essential oil, along with the use of routine anti-nausea/vomiting drugs, can reduce nausea and vomiting in the acute phase of chemotherapy.
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引用次数: 12
An Investigation of the Relationship between Non-Alcoholic Fatty Liver and Corticosteroid Use 非酒精性脂肪肝与皮质类固醇使用关系的研究
Q4 Medicine Pub Date : 2018-09-10 DOI: 10.18869/ACADPUB.JBUMS.20.9.61
A. Hemmatipour, A. Hatami, H. Aminifar, A. Jahangirmehr, I. Naderzadeh, Shahram Baraz
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引用次数: 0
تاثیر هشت هفته تمرین در آب بر SIRT1، PGC-1α و درصد چربی در مردان چاق
Q4 Medicine Pub Date : 2018-09-10 DOI: 10.18869/ACADPUB.JBUMS.20.9.55
محمود سلطانی, امیر رشیدلمیر, مهرداد فتحی, مهدی قهرمانی مقدم
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引用次数: 1
期刊
Journal of Babol University of Medical Sciences
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