{"title":"ژنهای چسبندگی بینسلولی (ica) مرتبط با تشکیل بیوفیلم و اسلایم در ایزولههای بالینی استافیلوکوکوس اورئوس حامل ژن mecA","authors":"ندا یوسفی نوجوکامبری, سجاد یزدان ستاد, عبدالله اردبیلی, مرتضی صاکی, احسان نجاری","doi":"10.18869/acadpub.jbums.20.6.27","DOIUrl":"https://doi.org/10.18869/acadpub.jbums.20.6.27","url":null,"abstract":"","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"12 1","pages":"27-35"},"PeriodicalIF":0.0,"publicationDate":"2018-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74921545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-10DOI: 10.18869/ACADPUB.JBUMS.20.6.62
Davood Sadeghi, F. Ebrahimi, M. Zeinoddini, Y. Tarverdizadeh, Mostafa Bakhshi, MJ Bageripor, SM Agaii
BACKGROUND AND OBJECTIVE: Ricin toxin is a heterodimer glycoprotein which, due to its high toxicity, is used as a bioterrorism agent. Immunogenicity studies against ricin are now focused on two subunit vaccine candidates, including RiVax and RVEc. These studies have examined the vaccine candidate immunization as an alone and in combination with adjuvant, however, there is not a published study on the immunogenicity evaluation of the candidate vaccine through the delivery by nanoparticles. The aim of this study was preparation and evaluation of RiVax recombinant vaccine-loading in chitosan nanoparticles. METHODS: In this experimental study, After transferring the RiVax gene to the bacterium, inducing the expression and purification of the RiVax protein by affinity chromatography column, the RiVax protein was loaded with Ionic Gelation method in chitosan nanoparticles. Then, the properties of nanoparticles including size, morphology, loading percentage and release pattern of RiVax protein from nanoparticles and stability of this protein during acidic loading conditions in nanoparticles by SDS-PAGE were evaluated. Also, Immunization study were performed on 3 mouse groups (n=4/group) by RiVax protein, Nanoparticles containing protein and phosphate buffer. FINDING: The results of this study showed that the nanoparticles containing protein had a size of 178 nm and a Zeta potential of +27.8 MV and a polydispersity index of 0.193. Also, according to SDS-PAGE results, it was found that the RiVax recombinant protein was denatured during the process of preparing the chitosan nanoparticles. CONCLUSION: The results of this study showed that the RiVax protein has been unstable in acidic conditions for the production of chitosan nanoparticles and Ionic Gelation method is not suitable for loading this protein in chitosan nanoparticles.
{"title":"Preparation and Evaluation of Rivax Protein Loading in Chitosan Nanoparticles","authors":"Davood Sadeghi, F. Ebrahimi, M. Zeinoddini, Y. Tarverdizadeh, Mostafa Bakhshi, MJ Bageripor, SM Agaii","doi":"10.18869/ACADPUB.JBUMS.20.6.62","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.6.62","url":null,"abstract":"BACKGROUND AND OBJECTIVE: Ricin toxin is a heterodimer glycoprotein which, due to its high toxicity, is used as a bioterrorism agent. Immunogenicity studies against ricin are now focused on two subunit vaccine candidates, including RiVax and RVEc. These studies have examined the vaccine candidate immunization as an alone and in combination with adjuvant, however, there is not a published study on the immunogenicity evaluation of the candidate vaccine through the delivery by nanoparticles. The aim of this study was preparation and evaluation of RiVax recombinant vaccine-loading in chitosan nanoparticles. METHODS: In this experimental study, After transferring the RiVax gene to the bacterium, inducing the expression and purification of the RiVax protein by affinity chromatography column, the RiVax protein was loaded with Ionic Gelation method in chitosan nanoparticles. Then, the properties of nanoparticles including size, morphology, loading percentage and release pattern of RiVax protein from nanoparticles and stability of this protein during acidic loading conditions in nanoparticles by SDS-PAGE were evaluated. Also, Immunization study were performed on 3 mouse groups (n=4/group) by RiVax protein, Nanoparticles containing protein and phosphate buffer. FINDING: The results of this study showed that the nanoparticles containing protein had a size of 178 nm and a Zeta potential of +27.8 MV and a polydispersity index of 0.193. Also, according to SDS-PAGE results, it was found that the RiVax recombinant protein was denatured during the process of preparing the chitosan nanoparticles. CONCLUSION: The results of this study showed that the RiVax protein has been unstable in acidic conditions for the production of chitosan nanoparticles and Ionic Gelation method is not suitable for loading this protein in chitosan nanoparticles.","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"48 1","pages":"62-69"},"PeriodicalIF":0.0,"publicationDate":"2018-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87550344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-10DOI: 10.18869/ACADPUB.JBUMS.20.6.7
Y. Pasha, A. Salarmanesh, S. Khafri, S. Mouodi, A. Arzani
{"title":"The Effect of Kangaroo Mother Care on Mental Health of Mothers with Premature Infants","authors":"Y. Pasha, A. Salarmanesh, S. Khafri, S. Mouodi, A. Arzani","doi":"10.18869/ACADPUB.JBUMS.20.6.7","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.6.7","url":null,"abstract":"","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"1 1","pages":"7-13"},"PeriodicalIF":0.0,"publicationDate":"2018-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79567282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-10DOI: 10.18869/ACADPUB.JBUMS.20.6.20
M. Ghorbani, M. Hojjati
J Babol Univ Med Sci; 20(6); June 2018; PP: 20-26 Received: Nov 4 2017, Revised: Jan 18 2018, Accepted: Feb 26 2018. ABSTRACT BACKGROUND AND OBJECTIVE: Immune platelet resistance is a condition in which antibodies are produced against platelet antigens and cause damage to injected platelets by phagocytes and macrophages. The aim of this study is to evaluate the efficacy of flow cytometry in predicting the results of platelet injections and platelet resistance and selecting compatible platelet for patients. METHODS: This case-control study was performed on 15 patients with acute myeloid leukemia (AML) with two or multiple injections of platelets and 15 healthy subjects without a history of platelet injection. After marking the platelets with 5-Chloromethylfluorescein diacetate (CMFDA) and their adjacency to the serum of patients, the amount of phagocytosis of platelets by monocytes was assessed in the two groups. FINDINGS: The mean phagocytic power of platelets by monocyte was 18.27 ± 2.86% in the control group, 68.47 ± 10.40% in the group of patients with immune platelet resistance, and 36.73 ± 15.21 in the group of patients without immune platelet resistance (p = 0.001). In addition, there was a significant negative correlation between phagocytic power of platelets by monocyte and Corrected Count Increment (CCI) at 1 and 24 hours (p = 0.001). CONCLUSION: Based on the results of this study and considering the high sensitivity of the flow cytometric method, the use of CMFDA is highly appropriate for evaluating platelet studies, and it can also be used for platelet crossmatch by flow cytometry. KEY WORD: Platelet Resistance, Flow Cytometry, CCI, Phagocytosis, 5-Chloromethylfluorescein diacetate.
{"title":"Evaluating the Performance of Flow Cytometric Method in Identification of Platelet Resistance in Patients with Acute Myeloid Leukemia (AML)","authors":"M. Ghorbani, M. Hojjati","doi":"10.18869/ACADPUB.JBUMS.20.6.20","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.6.20","url":null,"abstract":"J Babol Univ Med Sci; 20(6); June 2018; PP: 20-26 Received: Nov 4 2017, Revised: Jan 18 2018, Accepted: Feb 26 2018. ABSTRACT BACKGROUND AND OBJECTIVE: Immune platelet resistance is a condition in which antibodies are produced against platelet antigens and cause damage to injected platelets by phagocytes and macrophages. The aim of this study is to evaluate the efficacy of flow cytometry in predicting the results of platelet injections and platelet resistance and selecting compatible platelet for patients. METHODS: This case-control study was performed on 15 patients with acute myeloid leukemia (AML) with two or multiple injections of platelets and 15 healthy subjects without a history of platelet injection. After marking the platelets with 5-Chloromethylfluorescein diacetate (CMFDA) and their adjacency to the serum of patients, the amount of phagocytosis of platelets by monocytes was assessed in the two groups. FINDINGS: The mean phagocytic power of platelets by monocyte was 18.27 ± 2.86% in the control group, 68.47 ± 10.40% in the group of patients with immune platelet resistance, and 36.73 ± 15.21 in the group of patients without immune platelet resistance (p = 0.001). In addition, there was a significant negative correlation between phagocytic power of platelets by monocyte and Corrected Count Increment (CCI) at 1 and 24 hours (p = 0.001). CONCLUSION: Based on the results of this study and considering the high sensitivity of the flow cytometric method, the use of CMFDA is highly appropriate for evaluating platelet studies, and it can also be used for platelet crossmatch by flow cytometry. KEY WORD: Platelet Resistance, Flow Cytometry, CCI, Phagocytosis, 5-Chloromethylfluorescein diacetate.","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"67 1","pages":"20-26"},"PeriodicalIF":0.0,"publicationDate":"2018-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78143236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-10DOI: 10.18869/ACADPUB.JBUMS.20.6.53
S. Sadeghi, F. J. Ansari, H. Jalili
BACKGROUND AND OBJECTIVE: Probiotics are living microorganisms whose adequate intake has shown healthful effects in the host body and have been suggested to have beneficial effects in the prevention and treatment of many diseases. This study was conducted to investigate the obstacles and challenges of probiotic products in the production process and their effects on human health. METHODS: For data collection in this review article, articles containing one of the terms “probiotic”, “lactobacillus”, “bifidobacterium”, “biogenic amine” and “antibiotic resistance” from 1990 to 2017 were searched and reviewed at Thomson Reuters, Pubmed, Scopus, Science Direct and Islamic World Science Citation Center(ISC). FINDING: Research has shown that systematic infections and chronic diseases, over-stimulation of the immune system, transfer of antibiotic resistance genes, production of biogenic amines and D-lactic acidosis, lack of survival and sustainability of microorganisms and ultimately the change in the taste and flavor of probiotic products are among the obstacles and challenges facing the production of probiotics. The use of bifidobacterium to transfer antibiotic resistance genes is safer than other microorganisms for the production of probiotic products. CONCLUSION: Based on the results of this study, probiotics are only safe in healthy people, although they are very useful for human health, but their use in children, pregnant women and people with a weakened immune system causes
背景与目的:益生菌是一种活的微生物，其充足的摄入在宿主体内显示出健康作用，并被认为在预防和治疗许多疾病方面具有有益作用。本研究旨在探讨益生菌产品在生产过程中的障碍和挑战及其对人体健康的影响。方法:本综述文章的数据收集，在Thomson Reuters、Pubmed、Scopus、Science Direct和Islamic World Science Citation Center(ISC)检索并回顾了1990 - 2017年间包含“益生菌”、“乳酸菌”、“双歧杆菌”、“生物胺”和“抗生素耐药性”等术语的文章。发现:研究表明，系统性感染和慢性疾病、免疫系统的过度刺激、抗生素耐药基因的转移、生物胺和d -乳酸酸中毒的产生、微生物缺乏生存和可持续性以及最终改变益生菌产品的味道和风味是益生菌生产面临的障碍和挑战。使用双歧杆菌转移抗生素抗性基因比其他微生物生产益生菌产品更安全。结论:基于本研究的结果，益生菌仅对健康人群是安全的，虽然它们对人体健康非常有用，但它们在儿童、孕妇和免疫系统较弱的人群中的使用会导致
{"title":"Obstacles and Challenges in the Use of Probiotics","authors":"S. Sadeghi, F. J. Ansari, H. Jalili","doi":"10.18869/ACADPUB.JBUMS.20.6.53","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.6.53","url":null,"abstract":"BACKGROUND AND OBJECTIVE: Probiotics are living microorganisms whose adequate intake has shown healthful effects in the host body and have been suggested to have beneficial effects in the prevention and treatment of many diseases. This study was conducted to investigate the obstacles and challenges of probiotic products in the production process and their effects on human health. METHODS: For data collection in this review article, articles containing one of the terms “probiotic”, “lactobacillus”, “bifidobacterium”, “biogenic amine” and “antibiotic resistance” from 1990 to 2017 were searched and reviewed at Thomson Reuters, Pubmed, Scopus, Science Direct and Islamic World Science Citation Center(ISC). FINDING: Research has shown that systematic infections and chronic diseases, over-stimulation of the immune system, transfer of antibiotic resistance genes, production of biogenic amines and D-lactic acidosis, lack of survival and sustainability of microorganisms and ultimately the change in the taste and flavor of probiotic products are among the obstacles and challenges facing the production of probiotics. The use of bifidobacterium to transfer antibiotic resistance genes is safer than other microorganisms for the production of probiotic products. CONCLUSION: Based on the results of this study, probiotics are only safe in healthy people, although they are very useful for human health, but their use in children, pregnant women and people with a weakened immune system causes","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"759 1","pages":"53-61"},"PeriodicalIF":0.0,"publicationDate":"2018-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85427280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-10DOI: 10.18869/ACADPUB.JBUMS.20.6.70
P. Amri
J Babol Univ Med Sci; 20(6); Jun 2018; PP: 70-5 Received: Aug 31 2017, Revised: Mar 3 2018, Accepted: May 7 2018. ABSTRACT BACKGROUND AND OBJECTIVE: Drowning is a process of respiratory impairment due to the full immersion under fluids that about one third of patients with drowning experience pulmonary edema. In this article, two patients with acute pulmonary edema after drowning due to seizure who were admitted to the ICU department at Ayatollah Rouhani Hospital in Babol have been presented. CASE REPORT: An 18-year-old man with a history of epilepsy was drowned while swimming in the pool after a seizure. Due to hypoxia, he was treated with supplemental oxygen and NIV for 12 hours. After partial recovery, he was treated with oxygen for three days. The patient on the fourth day was discharged with a good general condition. Second patient: An 36-year old man, with a previous history of brain trauma was drowned while swimming in the sea after a seizure. The patient was intubated due to severe hypoxemia despite administration of oxygen (pao2 = 44mmHg) and low blood pressure (BP = 80 / 50mmHg), and was transferred to ICU at Ayatollah Rouhani Hospital. The patient was treated for mechanical ventilation and positive end expiratory pressure (PEEP) for 12 days. After recovery, he was separated from the ventilator and was discharged on the 14th day. CONCLUSION: In acute pulmonary edema after drowning, administration of oxygen and non-invasive ventilation is recommended. In the absence of response, tracheal intubation and invasive mechanical ventilation are recommended.
{"title":"Recovery of Acute Pulmonary Edema Following Drowning Due to Seizure: Report of Two Cases","authors":"P. Amri","doi":"10.18869/ACADPUB.JBUMS.20.6.70","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.6.70","url":null,"abstract":"J Babol Univ Med Sci; 20(6); Jun 2018; PP: 70-5 Received: Aug 31 2017, Revised: Mar 3 2018, Accepted: May 7 2018. ABSTRACT BACKGROUND AND OBJECTIVE: Drowning is a process of respiratory impairment due to the full immersion under fluids that about one third of patients with drowning experience pulmonary edema. In this article, two patients with acute pulmonary edema after drowning due to seizure who were admitted to the ICU department at Ayatollah Rouhani Hospital in Babol have been presented. CASE REPORT: An 18-year-old man with a history of epilepsy was drowned while swimming in the pool after a seizure. Due to hypoxia, he was treated with supplemental oxygen and NIV for 12 hours. After partial recovery, he was treated with oxygen for three days. The patient on the fourth day was discharged with a good general condition. Second patient: An 36-year old man, with a previous history of brain trauma was drowned while swimming in the sea after a seizure. The patient was intubated due to severe hypoxemia despite administration of oxygen (pao2 = 44mmHg) and low blood pressure (BP = 80 / 50mmHg), and was transferred to ICU at Ayatollah Rouhani Hospital. The patient was treated for mechanical ventilation and positive end expiratory pressure (PEEP) for 12 days. After recovery, he was separated from the ventilator and was discharged on the 14th day. CONCLUSION: In acute pulmonary edema after drowning, administration of oxygen and non-invasive ventilation is recommended. In the absence of response, tracheal intubation and invasive mechanical ventilation are recommended.","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"189 1","pages":"70-75"},"PeriodicalIF":0.0,"publicationDate":"2018-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74415254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-10DOI: 10.18869/ACADPUB.JBUMS.20.6.46
M. Salehi, Mohebbi, M. Karkhane, Shabnam Kazemian, P. Azimzadeh, M. S. Niasar, A. Sharifian, Zali
BACKGROUND AND OBJECTIVE: Interleukin 18 is a member of the cytokines that play an important role in the Th1-mediated immune response by inducing interferon-gamma activity in collaboration with Interleukin-12 (IL-18). Interleukin 12 and Interleukin 18 can play an important role in purifying viruses. Considering the importance of IL-18, this study was conducted to investigate the relationship between Interleukin-18 Gene polymorphism (-607 C/A: rs1946518) and the susceptibility to chronic hepatitis B infection. METHODS: In this case-control study, the genomic DNA of 115 patients with chronic hepatitis B (with positive results of HBsAg and Anti-HBcAb serology testing) and 115 non-HBV-infected controls (negative results of HBsAg and AntiHbcAb serology testing and no history of liver disease) was extracted by salting-out method and the genotype of singlenucleotide polymorphism (-607 C / A: rs1946518) was sequenced using PCR-RFLP method. FINDING: The genotype frequency of TT, GT, and GG in patients was 40%, 49.6%, and 10.4% in patients, and 41.7%, 42.6%, and 15.7% in the control group, respectively. No significant difference was found between the patients group and the control group. CONCLUSION: Based on the results of this study, there was no clear relationship between IL-18 polymorphism and the potential for chronic hepatitis B infection. Therefore, this polymorphism cannot be a potential factor for chronic hepatitis B.
背景与目的:白细胞介素18是一种细胞因子，通过与白细胞介素12 (IL-18)协同诱导干扰素γ活性，在th1介导的免疫应答中发挥重要作用。白细胞介素12和白细胞介素18在病毒纯化中起重要作用。考虑到IL-18的重要性，本研究探讨白细胞介素-18基因多态性(-607 C/A: rs1946518)与慢性乙型肝炎感染易感性的关系。方法:采用盐析法提取115例慢性乙型肝炎患者(HBsAg和Anti-HBcAb血清学检测结果阳性)和115例非hbv感染对照(HBsAg和AntiHbcAb血清学检测结果阴性，无肝病史)的基因组DNA，采用PCR-RFLP法测序单核苷酸多态性基因型(-607 C / A: rs1946518)。发现:患者中TT、GT和GG基因型频率分别为40%、49.6%和10.4%，对照组中分别为41.7%、42.6%和15.7%。患者组与对照组无明显差异。结论:基于本研究的结果，IL-18多态性与慢性乙型肝炎感染的可能性之间没有明确的关系。因此，这种多态性不可能是慢性乙型肝炎的潜在因素。
{"title":"Lack of Genetic Association between Interleukin-18 Gene Polymorphism (rs1946518) and Chronic Hepatitis B Infection","authors":"M. Salehi, Mohebbi, M. Karkhane, Shabnam Kazemian, P. Azimzadeh, M. S. Niasar, A. Sharifian, Zali","doi":"10.18869/ACADPUB.JBUMS.20.6.46","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.6.46","url":null,"abstract":"BACKGROUND AND OBJECTIVE: Interleukin 18 is a member of the cytokines that play an important role in the Th1-mediated immune response by inducing interferon-gamma activity in collaboration with Interleukin-12 (IL-18). Interleukin 12 and Interleukin 18 can play an important role in purifying viruses. Considering the importance of IL-18, this study was conducted to investigate the relationship between Interleukin-18 Gene polymorphism (-607 C/A: rs1946518) and the susceptibility to chronic hepatitis B infection. METHODS: In this case-control study, the genomic DNA of 115 patients with chronic hepatitis B (with positive results of HBsAg and Anti-HBcAb serology testing) and 115 non-HBV-infected controls (negative results of HBsAg and AntiHbcAb serology testing and no history of liver disease) was extracted by salting-out method and the genotype of singlenucleotide polymorphism (-607 C / A: rs1946518) was sequenced using PCR-RFLP method. FINDING: The genotype frequency of TT, GT, and GG in patients was 40%, 49.6%, and 10.4% in patients, and 41.7%, 42.6%, and 15.7% in the control group, respectively. No significant difference was found between the patients group and the control group. CONCLUSION: Based on the results of this study, there was no clear relationship between IL-18 polymorphism and the potential for chronic hepatitis B infection. Therefore, this polymorphism cannot be a potential factor for chronic hepatitis B.","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"7 1","pages":"46-52"},"PeriodicalIF":0.0,"publicationDate":"2018-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82276527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-10DOI: 10.18869/ACADPUB.JBUMS.20.6.41
M. Safabakhsh, M. Johari, Ali Bijani, S. Haghanifar
BACKGROUND AND OBJECTIVE: Soft tissue calcification is a relatively common issue in panoramic radiography. Some of these calcifications may have non-specific clinical symptoms as feeling of foreign body, dysphagia, otalgia and non-reflective cough. Therefore, for correct diagnosis and avoiding incorrect and excess treatments it’s necessary to have information about prevalence of these calcifications in regional populations. This study aimed to determine the prevalence of soft tissue calcification in panoramic radiographs in a selected population in northern Iran. METHODS: In this cross sectional study, panoramic radiographs of 5000 patients referring to Oral & Maxillofacial radiology department of Babol dental school from 2014 to 2017 were examined. Radiographs were evaluated for the presence of any calcification, and their prevalence and their relationship with age were evaluated in two groups of under and over 40 years of age and gender. FINDING: The prevalence of the observed soft tissue calcifications including calcification of stylohyoid ligands was 484 cases (9.7%), tonsilolith 52 cases (1%), calcification of lymph nodes 9 cases (0.2%), calcification of carotid artery 22 cases (0.4%) and thyroid cartilage calcification was 17 cases (0.3%). No cases of rhinolith, antrolith, sialolith and phlebolitis were found. The amount of tonsilolith (34 to 18 cases) and lymph node calcification (7 versus 2 cases) were significantly higher in men. (p=0.002 and p =0.048). Also, the prevalence of calcification of stylohyoid ligament (290 versus 194 cases) (p=0.001), tonsilolith (13% vs. 39 cases) (p=0.001), calcification of carotid artery (18 versus 4) (p=0.001), and thyroid (14 versus 3) (p=0.003) were significantly relevant with age. CONCLUSION: The results of this study showed that soft tissue calcifications are prevalent and the most common is stylohyoid ligament calcification.
{"title":"Prevalence of Soft Tissue Calcification in Panoramic Radiographs in Northern of Iran","authors":"M. Safabakhsh, M. Johari, Ali Bijani, S. Haghanifar","doi":"10.18869/ACADPUB.JBUMS.20.6.41","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.6.41","url":null,"abstract":"BACKGROUND AND OBJECTIVE: Soft tissue calcification is a relatively common issue in panoramic radiography. Some of these calcifications may have non-specific clinical symptoms as feeling of foreign body, dysphagia, otalgia and non-reflective cough. Therefore, for correct diagnosis and avoiding incorrect and excess treatments it’s necessary to have information about prevalence of these calcifications in regional populations. This study aimed to determine the prevalence of soft tissue calcification in panoramic radiographs in a selected population in northern Iran. METHODS: In this cross sectional study, panoramic radiographs of 5000 patients referring to Oral & Maxillofacial radiology department of Babol dental school from 2014 to 2017 were examined. Radiographs were evaluated for the presence of any calcification, and their prevalence and their relationship with age were evaluated in two groups of under and over 40 years of age and gender. FINDING: The prevalence of the observed soft tissue calcifications including calcification of stylohyoid ligands was 484 cases (9.7%), tonsilolith 52 cases (1%), calcification of lymph nodes 9 cases (0.2%), calcification of carotid artery 22 cases (0.4%) and thyroid cartilage calcification was 17 cases (0.3%). No cases of rhinolith, antrolith, sialolith and phlebolitis were found. The amount of tonsilolith (34 to 18 cases) and lymph node calcification (7 versus 2 cases) were significantly higher in men. (p=0.002 and p =0.048). Also, the prevalence of calcification of stylohyoid ligament (290 versus 194 cases) (p=0.001), tonsilolith (13% vs. 39 cases) (p=0.001), calcification of carotid artery (18 versus 4) (p=0.001), and thyroid (14 versus 3) (p=0.003) were significantly relevant with age. CONCLUSION: The results of this study showed that soft tissue calcifications are prevalent and the most common is stylohyoid ligament calcification.","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"49 1","pages":"41-45"},"PeriodicalIF":0.0,"publicationDate":"2018-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76640014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-10DOI: 10.18869/ACADPUB.JBUMS.20.6.14
مریم نظرزاده ده بزرگی, مریم قاسمپور, غزاله احمدی, ثریا خفری
{"title":"مقایسه چای سبز و سیاه با فلوراید در ریزسختی و پیشگیری از دمینرالیزاسیون مینای دندان های شیری","authors":"مریم نظرزاده ده بزرگی, مریم قاسمپور, غزاله احمدی, ثریا خفری","doi":"10.18869/ACADPUB.JBUMS.20.6.14","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.6.14","url":null,"abstract":"","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"43 1","pages":"14-19"},"PeriodicalIF":0.0,"publicationDate":"2018-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89572256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-05-15DOI: 10.18869/ACADPUB.JBUMS.20.5.7
H. Shahrahmani, Ns Kariman, S. Jannesari, M. Rafieian-kopaei, M. Mirzaei, N. Shahrahmani
BACKGROUND AND OBJECTIVE: Delay in recovery of episiotomy can lead to infection and persistence of perineal pain. Perineal pain is a stressful problem for primiparous women and has a negative effect on their function.The present study was conducted to determine the effect of Green tea ointment on the healing process of episiotomy. METHODS: This three-blind clinical trial was conducted on 60 primiparous participated in this research, were divided in two groups: Green tea ointment and placebo ointment. According to the routine of the hospital, 500 mg capsule cephalexin was given to all mothers every six hours for seven days. Mothers used an ointments every 12 hours for a period of ten days in the area of sutures. Wound healing was measured on the fifth and tenth day after delivery using REEDA scale. FINDINGS: There was no significant difference in demographic features and obstetric variables (for example age and weight newborn). Before the intervention, two groups did not have a significant difference in score of the perineal evaluation scale (p=0.475). The average of this scale on the fifth day in the green tea group was (1.83±1.147) and in placebo group it was (3.33±1.155) on the 10th day, the average of the perineal evaluation scale was (1.2±0.805) for the green tea group and (2.63±1.066) for the placebo group. The average of REEDA scores on the 5th and 10th day after delivery was significantly different between the two groups(p<0.00001) CONCLUSION: Green tea can improve episiotomy wound healing, due to its healing properties.
{"title":"The Effect of Camellia Sinensis Ointment on Perineal Wound Healing in Primiparous Women","authors":"H. Shahrahmani, Ns Kariman, S. Jannesari, M. Rafieian-kopaei, M. Mirzaei, N. Shahrahmani","doi":"10.18869/ACADPUB.JBUMS.20.5.7","DOIUrl":"https://doi.org/10.18869/ACADPUB.JBUMS.20.5.7","url":null,"abstract":"BACKGROUND AND OBJECTIVE: Delay in recovery of episiotomy can lead to infection and persistence of perineal pain. Perineal pain is a stressful problem for primiparous women and has a negative effect on their function.The present study was conducted to determine the effect of Green tea ointment on the healing process of episiotomy. \u0000METHODS: This three-blind clinical trial was conducted on 60 primiparous participated in this research, were divided \u0000in two groups: Green tea ointment and placebo ointment. According to the routine of the hospital, 500 mg capsule \u0000cephalexin was given to all mothers every six hours for seven days. Mothers used an ointments every 12 hours for a \u0000period of ten days in the area of sutures. Wound healing was measured on the fifth and tenth day after delivery using \u0000REEDA scale. \u0000FINDINGS: There was no significant difference in demographic features and obstetric variables (for example age and \u0000weight newborn). Before the intervention, two groups did not have a significant difference in score of the perineal \u0000evaluation scale (p=0.475). The average of this scale on the fifth day in the green tea group was (1.83±1.147) and in \u0000placebo group it was (3.33±1.155) on the 10th day, the average of the perineal evaluation scale was (1.2±0.805) for the green tea group and (2.63±1.066) for the placebo group. The average of REEDA scores on the 5th and 10th day after \u0000delivery was significantly different between the two groups(p<0.00001) CONCLUSION: Green tea can improve episiotomy wound healing, due to its healing properties.","PeriodicalId":15108,"journal":{"name":"Journal of Babol University of Medical Sciences","volume":"10 1","pages":"7-15"},"PeriodicalIF":0.0,"publicationDate":"2018-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74915546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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