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Angiomatoid Fibrous Histiocytoma: Case Presentation with Review of Literature 血管瘤样纤维组织细胞瘤1例并文献复习
Q4 Medicine Pub Date : 2021-06-30 DOI: 10.3390/osteology1030012
Gerardo Cazzato, A. Colagrande, A. Cimmino, Mariella Silecchia, T. Lettini, L. Resta, G. Ingravallo
Angiomatoid fibrous histiocytoma is a rare neoplasm with an intermediate malignant potential, that mostly occurs in the subcutis and features varying proportions of epithelioid, ovoid and spindle cells in a nodular and syncytial growth pattern, with hemorrhagic pseudovascular spaces. Here, we report the clinical case of a 68-year-old man who presented with AFH on the right arm; the disease relapsed a few years after surgical excision. We also conduct a brief review of the literature, focusing on the biological and genetic characteristics and the differential diagnosis from other more or less similar entities.
血管瘤样纤维组织细胞瘤是一种罕见的具有中等恶性潜能的肿瘤,主要发生在皮下,以结节状和合胞生长模式的不同比例的上皮样细胞、卵形细胞和梭形细胞为特征,并伴有出血性假血管间隙。在这里,我们报告了一个68岁男性的临床病例,他表现为右臂AFH;这种疾病在手术切除几年后复发。我们还对文献进行了简要的回顾,重点是生物学和遗传特征以及与其他或多或少相似实体的鉴别诊断。
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引用次数: 1
Quality of Mini C-Arm Imaging in Post-Reduction Evaluation of Distal Radius Fractures 迷你c臂成像在桡骨远端骨折复位后评价中的质量
Q4 Medicine Pub Date : 2021-06-23 DOI: 10.3390/osteology1030011
W. Daner, P. Ryan, G. Domson, A. Sima, J. Isaacs
Following closed reduction of distal radius fractures, formal radiographs are often obtained despite previous verification on fluoroscopy. A prospective collection of 60 consecutive distal radius fractures was obtained to compare the quality of the fluoroscopic images obtained from a mini C-arm versus formal radiographs. The images were reviewed by six orthopedic surgeons and one radiologist. The likelihood that further imaging was deemed necessary to guide treatment decisions was 1.9 times higher in the mini C-arm imaging cohort (95% CI: 1:34, 2.69). While mini C-arm remains a useful reduction aid, formal radiographs should still be obtained to document post-reduction alignment and to guide treatment decisions.
在桡骨远端骨折闭合复位后,尽管先前有透视检查证实,但仍需进行正式的x线片检查。对60例连续桡骨远端骨折进行前瞻性收集,以比较迷你c型臂和正规x线片所获得的透视图像的质量。六位骨科医生和一位放射科医生审查了这些图像。在迷你c臂成像队列中,进一步成像被认为有必要指导治疗决策的可能性高出1.9倍(95% CI: 1:34, 2.69)。虽然迷你c型臂仍然是一种有用的复位辅助手段,但仍应获得正式的x线片,以记录复位后的对齐并指导治疗决策。
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引用次数: 1
Influence of Gender on Occurrence of Aseptic Loosening and Recurrent PJI after Revision Total Knee Arthroplasty 性别对改良全膝关节置换术后无菌性松动及PJI复发的影响
Q4 Medicine Pub Date : 2021-05-17 DOI: 10.3390/OSTEOLOGY1020010
A. Kienzle, S. Walter, Y. Palmowski, S. Kirschbaum, Lara Biedermann, P. von Roth, C. Perka, Michael Müller
Background: Periprosthetic joint infection (PJI) is a common yet severe complication after total knee arthroplasty (TKA). Surgical intervention and antibiotic therapy are obligatory to achieve successful, infection-free outcome. Compared to the outcomes after primary TKA, prosthesis failure rates are drastically increased after PJI-dependent revision surgery. Recurrent PJI and aseptic loosening are the most common reasons for prosthesis failure after revision TKA. An open question is the influence of the patients’ gender on long-term prosthesis survival after revision surgery. Additionally, it is unknown whether gender-related parameters and risk factors or differences in treatment are responsible for potential differences in outcome after revision arthroplasty. Patients and Methods: In this report, 109 patients that received TKA revision surgery due to PJI were retrospectively analyzed. We used clinical, paraclinical and radiological examinations to study the influence of gender on the long-term complications aseptic loosening and recurrent PJI after PJI-dependent revision arthroplasty. Results: While overall prosthesis failure rates and risk of recurrent PJI did not differ between genders, the long-term risk of aseptic loosening was significantly elevated in female patients. Postoperative coronal alignment was significantly more varus for women later diagnosed with aseptic loosening. Besides coronal alignment, no gender-dependent differences in clinical presentation or treatment were observed. Conclusions: Female patients displayed a significantly increased risk for aseptic loosening after PJI-dependent revision TKA. The observed gender-dependent differences in long-term outcome in our study support theories surrounding the role of bone metabolism in the development of aseptic loosening. Our data suggest that further research on a female design for PJI-dependent revision prostheses is warranted.
背景:假体周围关节感染(PJI)是全膝关节置换术(TKA)后常见但严重的并发症。手术干预和抗生素治疗是必要的,以达到成功,无感染的结果。与初次TKA后的结果相比,pji依赖性翻修手术后假体失败率急剧增加。复发性PJI和无菌性松动是改良TKA后假体失败的最常见原因。一个悬而未决的问题是患者的性别对修复术后长期假体存活的影响。此外,尚不清楚与性别相关的参数和危险因素或治疗的差异是否导致翻修关节置换术后结果的潜在差异。患者和方法:本报告回顾性分析109例因PJI而行TKA翻修手术的患者。我们通过临床、临床旁和影像学检查来研究性别对PJI依赖关节置换术后无菌性松动和复发性PJI的长期并发症的影响。结果:虽然假体总体失败率和复发性PJI的风险在性别之间没有差异,但女性患者无菌性松动的长期风险显著升高。对于后来诊断为无菌性松动的女性,术后冠状位排列明显更容易内翻。除了冠状排列外,没有观察到临床表现或治疗的性别差异。结论:女性患者在pji依赖性改良TKA后出现无菌性松动的风险显著增加。在我们的研究中观察到的长期结果的性别依赖差异支持了有关骨代谢在无菌性松动发展中的作用的理论。我们的数据表明,有必要进一步研究女性pji依赖修复假体的设计。
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引用次数: 5
Normative Values for Femoral Length, Tibial Length, and the Femorotibial Ratio in Adults Using Standing Full-Length Radiography 站立式全身x线摄影测定成人股骨长度、胫骨长度和股胫比的标准值
Q4 Medicine Pub Date : 2021-05-13 DOI: 10.3390/OSTEOLOGY1020009
S. Aitken
Knowledge of the normal length and skeletal proportions of the lower limb is required as part of the evaluation of limb length discrepancy. When measuring limb length, modern standing full-length digital radiographs confer a level of clinical accuracy interchangeable with that of CT imaging. This study reports a set of normative values for lower limb length using the standing full-length radiographs of 753 patients (61% male). Lower limb length, femoral length, tibial length, and the femorotibial ratio were measured in 1077 limbs. The reliability of the measurement method was tested using the intra-class correlation (ICC) of agreement between three observers. The mean length of 1077 lower limbs was 89.0 cm (range 70.2 to 103.9 cm). Mean femoral length was 50.0 cm (39.3 to 58.4 cm) and tibial length was 39.0 cm (30.8 to 46.5 cm). The median side-to-side difference was 0.4 cm (0.2 to 0.7, max 1.8 cm) between 324 paired limbs. The mean ratio of femoral length to tibial length for the study population was 1.28:1 (range 1.16 to 1.39). A moderately strong inverse linear relationship (r = −0.35, p < 0.001, Pearson’s) was identified between tibial length and the corresponding femorotibial ratio. The PACS-based length measurement method used in this study displayed excellent inter-observer reliability (ICC of 0.99). This study presents a normal range of values for lower limb length in adults and is the first to identify a linear relationship between tibial length and the femorotibial ratio.
作为评估肢体长度差异的一部分,需要了解下肢的正常长度和骨骼比例。当测量肢体长度时,现代站立式全长数字x线片具有与CT成像可互换的临床精度水平。本研究报告了753例患者(61%为男性)站立全身x线片下肢长度的一组规范值。测量1077例下肢长、股骨长、胫骨长及股胫比。测量方法的可靠性是用三个观察者之间的一致性的类内相关(ICC)来检验的。1077例下肢平均长度为89.0 cm (70.2 ~ 103.9 cm)。股骨平均长度为50.0 cm (39.3 ~ 58.4 cm),胫骨平均长度为39.0 cm (30.8 ~ 46.5 cm)。324对四肢的中位侧差为0.4 cm(0.2 ~ 0.7,最大1.8 cm)。研究人群股骨长度与胫骨长度的平均比值为1.28:1(范围1.16至1.39)。胫骨长度与相应的股胫比之间存在中等强的逆线性关系(r = - 0.35, p < 0.001, Pearson’s)。本研究使用的基于pacs的长度测量方法显示出良好的观察者间信度(ICC为0.99)。这项研究提出了成人下肢长度的正常范围,并首次确定了胫骨长度与股胫比之间的线性关系。
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引用次数: 3
Bone and Joint Infections in Children and Adolescents in Luanda, Angola 安哥拉罗安达儿童和青少年的骨骼和关节感染
Q4 Medicine Pub Date : 2021-04-19 DOI: 10.3390/OSTEOLOGY1020008
M. Pääkkönen, T. Pelkonen, Guilhermino Joaquim, Luis Bernandino, T. Pöyhiä, I. Roine, H. Peltola
We reviewed the characteristics of children hospitalized for bone and joint infections in Luanda, Angola. In a retrospective chart review of 45 patients with childhood osteomyelitis or septic arthritis, 51% of the patients had sickle cell disease, and these patients presented with lower hemoglobin and needed blood transfusion more frequently (p < 0.05). Out of all patients, 64% underwent surgical procedures; a pathological fracture occurred in 31% of the patients.
我们回顾了安哥拉罗安达因骨骼和关节感染住院的儿童的特点。在对45例儿童骨髓炎或脓毒性关节炎患者的回顾性图表回顾中,51%的患者患有镰状细胞病,这些患者表现为血红蛋白较低,输血次数较多(p < 0.05)。在所有患者中,64%接受了外科手术;31%的患者发生病理性骨折。
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引用次数: 0
The Products of Bone Resorption and Their Roles in Metabolism: Lessons from the Study of Burns 骨吸收产物及其在代谢中的作用:来自烧伤研究的启示
Q4 Medicine Pub Date : 2021-04-01 DOI: 10.3390/OSTEOLOGY1020007
G. Klein
Surprisingly little is known about the factors released from bone during resorption and the metabolic roles they play. This paper describes what we have learned about factors released from bone, mainly through the study of burn injuries, and what roles they play in post-burn metabolism. From these studies, we know that calcium, phosphorus, and magnesium, along with transforming growth factor (TGF)-β, are released from bone following resorption. Additionally, studies in mice from Karsenty’s laboratory have indicated that undercarboxylated osteocalcin is also released from bone during resorption. Questions arising from these observations are discussed as well as a variety of potential conditions in which release of these factors could play a significant role in the pathophysiology of the conditions. Therapeutic implications of understanding the metabolic roles of these and as yet other unidentified factors are also raised. While much remains unknown, that which has been observed provides a glimpse of the potential importance of this area of study.
令人惊讶的是,人们对骨骼在吸收过程中释放的因子及其在代谢中的作用知之甚少。本文主要介绍了我们对骨释放因子的了解,主要是通过对烧伤损伤的研究,以及它们在烧伤后代谢中的作用。从这些研究中,我们知道钙、磷和镁,以及转化生长因子(TGF)-β,在骨吸收后释放出来。此外,Karsenty实验室对小鼠的研究表明,在骨吸收过程中,低羧化骨钙素也会从骨中释放出来。从这些观察中产生的问题被讨论,以及各种潜在的条件中,这些因素的释放可能在这些条件的病理生理学中发挥重要作用。还提出了了解这些和其他未确定因素的代谢作用的治疗意义。虽然仍有许多未知之处,但已观察到的情况提供了这一研究领域潜在重要性的一瞥。
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引用次数: 1
Comparative Evaluation of Primary Stability between Different Diameters Multi-Scale Roughness Dental Implant by Solid Rigid Polyurethane Simulation 固体硬质聚氨酯模拟不同直径多尺度粗糙度种植体初级稳定性的比较评价
Q4 Medicine Pub Date : 2021-03-12 DOI: 10.3390/OSTEOLOGY1010006
M. Tumedei, M. Petrini, A. Cipollina, Mariastella Di Carmine, A. Piattelli, A. Cucurullo, G. Iezzi
Background: Implant primary stability is determined by screw characteristics and surgical procedure. The aim of the present study was to evaluate, on a polyurethane model, the insertion torque (IT), removal torque (RT), and resonance frequency analysis (RFA) of multi-scale roughness dental implants of different diameters. Methods: Two implant sizes were tested on two polyurethane blocks (20 pounds per cubic foot (PCF) and 30 PCF): 3.0 diameter and 13 mm length and 5.0 diameter and 13 mm length. The IT, RT, and RFA were assessed. Results: A significant difference of IT and RT was present in favor of wider implants at both polyurethane densities. No statistical difference was present between the 5.0 diameter and 3.0 diameter implants at both polyurethane densities. A statistically increased RFA was reported for 5.0 implant 30 PCF polyurethane blocks. Conclusions: Multi-scale roughness dental implants of both diameters showed high insertion torque and primary stability on polyurethane blocks, which is valuable for implant loading protocols.
背景:植体的初始稳定性是由螺钉特性和手术方式决定的。本研究的目的是在聚氨酯模型上评估不同直径的多尺度粗糙种植体的插入扭矩(IT)、移除扭矩(RT)和共振频率分析(RFA)。方法:在两个聚氨酯块(20磅/立方英尺(PCF)和30磅/立方英尺)上测试两种种植体尺寸:3.0直径和13mm长和5.0直径和13mm长。评估IT、RT和RFA。结果:在两种聚氨酯密度下,IT和RT存在显著差异,有利于更宽的植入物。在两种聚氨酯密度下,5.0直径和3.0直径的植入物无统计学差异。据统计,5.0植入30 PCF聚氨酯块的RFA增加。结论:两种直径的多尺度粗糙度种植体在聚氨酯块上具有较高的插入扭矩和初步稳定性,对种植体加载方案具有重要价值。
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引用次数: 2
Isolated Medial Subtalar Joint Dislocation during Sports Activities: A Systematic Review of the Literature with Individual Participant Data Analysis 体育活动中孤立的内侧距下关节脱位:对文献的系统回顾和个体参与者数据分析
Q4 Medicine Pub Date : 2021-03-05 DOI: 10.3390/OSTEOLOGY1010005
C. Biz, Giovanni Baldin, Claudia Cappelletto, N. Bragazzi, P. Nicoletti, A. Crimì, P. Ruggieri
In athletes, one of the most common injuries is a sprained ankle. If the energy of the trauma is particularly high, this type of injury can lead to an isolated medial dislocation of the subtalar joint (STJ), a rare condition poorly described in the literature. The aim of this study was to verify if a reliable conservative treatment and a specific physiotherapy rehabilitation protocol in isolated medial dislocation of the STJ in athletes is described in the literature. A systematic review of the published literature of the last 11 years was performed by applying the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines using three databases: Pubmed, Scopus, and Web of Science. The keywords used were “(subtalar OR talocalcaneal) AND dislocation”. We considered only studies that included professional or amateur athletes (athletic patients). We used the American Orthopedic Foot and Ankle Society (AOFAS) scale, range of motion (ROM) of the subtalar and ankle joint, subtalar and talonavicular joint osteoarthritis, and patient feedback to evaluate their outcomes. A total of 12 studies were included in our review, with a total of 26 athletic patients. Sixteen of them had good results with the correlation between the duration of immobilisation and the outcomes. Nevertheless, due to the small number of patients included in the analysed studies on this subject in the literature, there is not yet a univocal clinical protocol to treat the isolated medial subtalar joint dislocation (STJD) warranting further research in the field.
在运动员中,最常见的伤病之一是扭伤脚踝。如果创伤的能量特别高,这种类型的损伤可导致孤立的距下关节内侧脱位(STJ),这是一种罕见的情况,文献中很少描述。本研究的目的是验证文献中是否描述了运动员孤立性STJ内侧脱位的可靠的保守治疗和特定的物理治疗康复方案。应用系统评价和荟萃分析首选报告项目(PRISMA)指南,使用Pubmed、Scopus和Web of Science三个数据库,对过去11年的已发表文献进行了系统评价。使用的关键词是“(距下或距跟骨)和脱位”。我们只考虑了包括专业或业余运动员(运动患者)的研究。我们使用美国骨科足踝协会(AOFAS)量表、距下关节和踝关节、距下关节和距舟关节骨性关节炎的活动范围(ROM)以及患者反馈来评估他们的结果。我们的综述共纳入了12项研究,共有26名运动员患者。其中16例有良好的结果,固定时间与结果之间存在相关性。然而,由于文献中关于该主题的分析研究中纳入的患者数量较少,目前尚没有一个明确的临床方案来治疗孤立性距下关节脱位(STJD),值得在该领域进一步研究。
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引用次数: 2
Complex Regional Pain Syndrome: Current Practice Management and Referral Trends in a Closed Healthcare System 复杂的区域性疼痛综合征:目前的实践管理和转诊趋势在一个封闭的医疗保健系统
Q4 Medicine Pub Date : 2020-12-31 DOI: 10.3390/osteology1010004
C. Zale, Joshua Hansen, P. Ryan
Background: Complex regional pain syndrome (CRPS) is a neurologic condition that can present with severe pain and dysfunction. Delay in treatment adversely affects outcomes. The purpose of this study is to evaluate patient outcomes as they relate to the time from diagnosis to pain management referral once the diagnosis of CRPS has been made in a closed healthcare system. Methods: A retrospective record review from a closed healthcare system was utilized for CRPS cases from 2010–2019. Demographics, injury pattern, surgeries, pain score, treatment modalities, occupational outcomes, and time to pain management referral were recorded. Results: There were 26 cases of CRPS that met inclusion criteria. The mean time from diagnosis to treatment was 55 days. 16/26 (61.5%) were medically discharged from the military. 23/26 (88.5%) were unable to return to full duty due to CRPS. There was no significant difference in the reported pain scores over time regardless of treatment (p = 0.76). A linear regression demonstrated a significantly higher Visual Analog Scale Pain Score (VAS) over time in patients that were medically discharged (p = 0.022). Conclusions: The mean delay in referral to the pain service was 55 days. The majority of patients (88.5%) did not return to full duty secondary to the diagnosis of CRPS, and 61.5% of patients required medical separation from active duty. Due to the negative impact that the diagnosis of CRPS has on occupational outcomes with a mean delay in referral of 55 days, clinics and providers should set up referral criteria and establish early pain pathways for patients diagnosed with CRPS.
背景:复杂区域疼痛综合征(CRPS)是一种神经系统疾病,可表现为严重的疼痛和功能障碍。治疗延误会对结果产生不利影响。本研究的目的是评估患者的结果,因为一旦在封闭的医疗保健系统中诊断出CRPS,他们就会从诊断到疼痛管理转诊的时间。方法:对2010-2019年封闭医疗系统的CRPS病例进行回顾性记录回顾。记录人口统计、损伤类型、手术、疼痛评分、治疗方式、职业结局和疼痛管理转诊时间。结果:26例CRPS符合纳入标准。从诊断到治疗的平均时间为55天。16/26(61.5%)因病退伍。23/26(88.5%)由于CRPS无法返回全职工作。无论治疗方式如何,报告的疼痛评分随时间变化无显著差异(p = 0.76)。线性回归显示,随着时间的推移,医学出院患者的视觉模拟量表疼痛评分(VAS)显著提高(p = 0.022)。结论:转介到疼痛服务的平均延迟为55天。大多数患者(88.5%)在诊断为CRPS后没有重返工作岗位,61.5%的患者需要医学分离。由于CRPS诊断对职业结局的负面影响,平均延迟转诊55天,诊所和提供者应该为诊断为CRPS的患者建立转诊标准和早期疼痛通路。
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引用次数: 0
Delayed Rehabilitation Protocol after Rotator Cuff Repair 肩袖修复后的延迟康复方案
Q4 Medicine Pub Date : 2020-12-26 DOI: 10.3390/osteology1010003
A. Berton, S. De Salvatore, V. Candela, G. Cortina, D. Lo Presti, C. Massaroni, S. Petrillo, V. Denaro
Rotator cuff tears are a frequent cause of shoulder pain that often require arthroscopic repair. After surgery an intense and well-studied rehabilitation protocol is needed to obtain the complete recovery of shoulder function. Fifty patients, who sustained arthroscopic rotator cuff repair for symptomatic, atraumatic and full-thickness supraspinatus tendon tear, were involved. According to our rehabilitation protocol, during the first four postoperative weeks, the arm was supported with an abduction sling pillow, and pendulum exercises, table slide and active elbow extension and flexion were conceded. Outcome measures (Oxford shoulder score (OSS), simple shoulder test (SST), patient-reported satisfaction), shoulder function (range of motion (ROM) and muscle strength), and MRI examination were evaluated. The mean OSS score and SST score increased from 16 to 30.2 and from 5.3 to 11.4, respectively. Patient-reported satisfaction was 96%. At 12 months, patients improved ROM and muscle strength. Postoperative passive anterior elevation was 176; external rotation averaged 47; internal rotation was 90. Postoperative muscle strength during anterior elevation was 8.3 ± 2.2 kg, internal rotation 6.8 ± 3 kg, external rotation 5.5 ± 2.3 kg. Five out of seven patients with recurrent tears evaluated their results as satisfactory. They reported improvements in terms of OSS and SST mean scores despite recurrent tears; therefore, they did not undergo revision surgery. The delayed postoperative physical therapy protocol was associated with improvements in the outcome measures and shoulder function compared to the preoperatory state and rotator cuff healing demonstrated by MRI.
肩袖撕裂是肩部疼痛的常见原因,通常需要关节镜修复。手术后,需要一个严格的、经过充分研究的康复方案来获得肩部功能的完全恢复。我们研究了50例因症状性、无伤性和全层冈上肌腱撕裂而进行关节镜下肩袖修复的患者。根据我们的康复方案,在术后前四周内,手臂由外展吊带枕支撑,并允许进行钟摆运动、桌子滑动和主动肘关节伸展和屈曲。结果测量(牛津肩关节评分(OSS)、简单肩关节测试(SST)、患者报告的满意度)、肩关节功能(活动度(ROM)和肌力)和MRI检查进行评估。平均OSS评分从16分上升到30.2分,平均SST评分从5.3分上升到11.4分。患者报告的满意度为96%。12个月时,患者的ROM和肌肉力量得到改善。术后被动前位抬高176;外旋平均47;内旋为90度。术后前抬高肌力8.3±2.2 kg,内旋6.8±3 kg,外旋5.5±2.3 kg。7名复发性流泪患者中有5名对治疗结果满意。他们报告了OSS和SST平均得分的改善,尽管反复流泪;因此,他们没有接受翻修手术。与术前状态和MRI显示的肩袖愈合相比,延迟术后物理治疗方案与预后指标和肩功能的改善有关。
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引用次数: 10
期刊
Clinical Osteology
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