Pub Date : 2018-02-01Epub Date: 2018-02-07DOI: 10.21037/ncri.2018.01.03
Wan-Xin Peng, Le-Tao Fan, Yin-Yuan Mo
{"title":"A link between a synonymous SNP and the clinical response to tyrosine kinase inhibitors.","authors":"Wan-Xin Peng, Le-Tao Fan, Yin-Yuan Mo","doi":"10.21037/ncri.2018.01.03","DOIUrl":"https://doi.org/10.21037/ncri.2018.01.03","url":null,"abstract":"","PeriodicalId":74314,"journal":{"name":"Non-coding RNA investigation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.21037/ncri.2018.01.03","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37242906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01Epub Date: 2018-01-17DOI: 10.21037/ncri.2018.01.01
Jen-Hao Yang, Myriam Gorospe
{"title":"Multi-leveled suppression of p53 function by HuR IncRNPs.","authors":"Jen-Hao Yang, Myriam Gorospe","doi":"10.21037/ncri.2018.01.01","DOIUrl":"10.21037/ncri.2018.01.01","url":null,"abstract":"","PeriodicalId":74314,"journal":{"name":"Non-coding RNA investigation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108584/pdf/nihms-984832.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36430379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01Epub Date: 2018-06-28DOI: 10.21037/ncri.2018.06.04
Nicholas Manguso, Armando E Giuliano, Hisashi Tanaka
Lung cancer remains the most common cause of cancer related death among both males and females globally accounting for 1.69 million deaths in 2015 (1). Of the different types of lung cancer, lung adenocarcinoma (LAC) is the most common (2). Given the prevalence and lethality of lung cancer the need to elucidate the mechanisms of this disease and to develop novel therapeutic targets remains paramount. The understanding of the biology and genetics of LAC is essential to learning more about this disease.
{"title":"circRNA meets gene amplification.","authors":"Nicholas Manguso, Armando E Giuliano, Hisashi Tanaka","doi":"10.21037/ncri.2018.06.04","DOIUrl":"https://doi.org/10.21037/ncri.2018.06.04","url":null,"abstract":"Lung cancer remains the most common cause of cancer related death among both males and females globally accounting for 1.69 million deaths in 2015 (1). Of the different types of lung cancer, lung adenocarcinoma (LAC) is the most common (2). Given the prevalence and lethality of lung cancer the need to elucidate the mechanisms of this disease and to develop novel therapeutic targets remains paramount. The understanding of the biology and genetics of LAC is essential to learning more about this disease.","PeriodicalId":74314,"journal":{"name":"Non-coding RNA investigation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.21037/ncri.2018.06.04","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36411695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-01Epub Date: 2017-12-13DOI: 10.21037/ncri.2017.12.01
Mackenzie Hagan, Mi Zhou, Muhammad Ashraf, Il-Man Kim, Huabo Su, Neal L Weintraub, Yaoliang Tang
Myogenic fate determination is important in skeletal muscle development, growth and repair. A variety of factors regulate myogenic cell determination via transcriptional and non-transcriptional mechanisms. Amongst these factors, long noncoding RNAs (lncRNAs) have gained considerable attention for their important roles in regulating myogenic differentiation and function. Many classes of lncRNAs have been discovered; various lncRNAs have been implicated in the regulation of myogenic cell fate determination and are the subject of this brief review.
{"title":"Long noncoding RNAs and their roles in skeletal muscle fate determination.","authors":"Mackenzie Hagan, Mi Zhou, Muhammad Ashraf, Il-Man Kim, Huabo Su, Neal L Weintraub, Yaoliang Tang","doi":"10.21037/ncri.2017.12.01","DOIUrl":"https://doi.org/10.21037/ncri.2017.12.01","url":null,"abstract":"<p><p>Myogenic fate determination is important in skeletal muscle development, growth and repair. A variety of factors regulate myogenic cell determination via transcriptional and non-transcriptional mechanisms. Amongst these factors, long noncoding RNAs (lncRNAs) have gained considerable attention for their important roles in regulating myogenic differentiation and function. Many classes of lncRNAs have been discovered; various lncRNAs have been implicated in the regulation of myogenic cell fate determination and are the subject of this brief review.</p>","PeriodicalId":74314,"journal":{"name":"Non-coding RNA investigation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.21037/ncri.2017.12.01","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35839610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-11-01Epub Date: 2017-11-17DOI: 10.21037/ncri.2017.11.02
David G Menter, Preeti Kanikarla-Marie, Michael Lam, Jennifer S Davis, Scott Kopetz
{"title":"Platelet microparticles: small payloads with profound effects on tumor growth.","authors":"David G Menter, Preeti Kanikarla-Marie, Michael Lam, Jennifer S Davis, Scott Kopetz","doi":"10.21037/ncri.2017.11.02","DOIUrl":"https://doi.org/10.21037/ncri.2017.11.02","url":null,"abstract":"","PeriodicalId":74314,"journal":{"name":"Non-coding RNA investigation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583804/pdf/nihms-984831.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37072035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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