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Nursing times最新文献

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Trailblazers 开拓者
Pub Date : 2020-05-20 DOI: 10.2307/j.ctv11hptz6.15
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引用次数: 0
Face to face. 面对面。
Pub Date : 2020-05-15 DOI: 10.7748/ns.9.5.52.s61
D. Payne
According to Zweig Group’s 2017 Valuation Survey, firms that underwent a valuation to prepare for a potential sale or merger had a median equity value/book value ratio of 3.8. Those done for the requirement of a buy/ sell agreement had a EV/BV ratio of 2.14. Valuations for internal ownership transfers had a EV/BV of 1.99 and those done in order to obtain financing were 1.88, along with those done to meet an ERISA/ESOP/IRS requirement. T R E N D L I N E S
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引用次数: 0
Extending the Boundaries of Care 扩大护理的范围
Pub Date : 2020-05-12 DOI: 10.4324/9781003085386
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引用次数: 0
Peter. 彼得。
Pub Date : 2020-04-28 DOI: 10.1163/2405-8262_rgg4_sim_024463
O. M. Bowmer
Submerged prehistoric landscapes are significant portions of the archaeological record that are just coming to light for many archaeologists. Researchers in Europe have largely led this wave
被淹没的史前景观是考古记录的重要组成部分,对许多考古学家来说,它们刚刚浮出水面。欧洲的研究人员在很大程度上引领了这一浪潮
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引用次数: 0
Prostate cancer. 前列腺癌症。
Pub Date : 2020-04-01 DOI: 10.1097/ju.0000000000000913
Pieters
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引用次数: 0
Temazepam. 羟基安定。
Pub Date : 2020-03-26 DOI: 10.4324/9781315825731-103
Louis A. Pagliaro, Ann Marie Pagliaro
In a single and multiple dose absorption, distribution, metabolism, and excretion (ADME) study, using 3H labeled drug, temazepam was well absorbed and found to have minimal (8%) first pass metabolism. There were no active metabolites formed and the only significant metabolite present in blood was the O-conjugate. The unchanged drug was 96% bound to plasma proteins. The blood level decline of the parent drug was biphasic with the short half-life ranging from 0.4 0.6 hours and the terminal half-life from 3.5 18.4 hours (mean 8.8 hours), depending on the study population and method of determination. Metabolites were formed with a half-life of 10 hours and excreted with a half-life of approximately 2 hours. Thus, formation of the major metabolite is the rate limiting step in the biodisposition of temazepam. There is no accumulation of metabolites. A dose-proportional relationship has been established for the area under the plasma concentration/time curve over the 15 30 mg dose range.
在一项单剂量和多剂量吸收、分布、代谢和排泄(ADME)研究中,使用3H标记的药物,替马西泮被很好地吸收,并发现具有最小(8%)的首过代谢。没有形成活性代谢产物,血液中存在的唯一重要代谢产物是O-缀合物。不变的药物96%与血浆蛋白结合。母体药物的血液水平下降是双相的,短半衰期为0.4至0.6小时,终半衰期为3.5至18.4小时(平均8.8小时),具体取决于研究人群和测定方法。代谢物的形成半衰期为10小时,排泄半衰期约为2小时。因此,主要代谢产物的形成是替马西泮生物分散的限速步骤。没有代谢物的积累。已经建立了在15-30mg剂量范围内血浆浓度/时间曲线下的面积的剂量比例关系。
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引用次数: 5
Teacher as Student 教师作为学生
Pub Date : 2020-02-18 DOI: 10.1287/orms.2005.05.05
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引用次数: 0
Best FRIENDS. 最好的朋友。
Pub Date : 2020-02-11 DOI: 10.2307/j.ctvp7d4z2.93
C. Lomas
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引用次数: 0
Fetal alcohol syndrome. 胎儿酒精综合征。
Pub Date : 2020-02-10 DOI: 10.32388/lq4gob
J. Wright
FASD is a continuum of physical, growth, and neurobehavioral abnormalities that occur as a result of prenatal exposure to alcohol and other disorders in FASD include: Partial fetal alcohol syndrome (PFAS)Alcohol-related birth defects (ARBD)Alcohol-related neurodevelopmental disorder (ARND)Diagnosis of FAS and other FASD is established by history and physical examination.Early recognition and treatment is crucial for better outcomes.Multidisciplinary team approach is recommended for management.
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引用次数: 1
Lead poisoning. 铅中毒。
Pub Date : 2020-02-10 DOI: 10.32388/wu9vr7
M. Antrobus
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引用次数: 0
期刊
Nursing times
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