1例Covid-19阳性患者的肺炎和肺毛霉菌病报告

Luv Sharma, Sumiti Gupta, Lalit Chopra, Pooja Dhamija
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摘要

在第二波冠状病毒病(Covid-19)之后,印度卫生和家庭福利部报告的毛霉病病例数量有所增加。截至2021年7月中旬,共报告了45 432例毛霉病,其中4252人死亡。毛霉病和其他真菌感染最常被视为机会性感染。它们存在于基础免疫力低下的人群中,要么是由于糖尿病、癌症(特别是血液系统恶性肿瘤)等原因,要么是长期/不合理使用某些药物(如类固醇)、用于治疗包括Covid-19在内的其他疾病的免疫抑制药物的副作用。印度卫生当局指出,虽然这不是一种新疾病,但在第二波开始时,其真实发病率尚不清楚,因为它不是一种必须报告的疾病。根据报告,毛霉菌病最常见的表现包括鼻-脑(77.6%)、皮肤(4.3%)和肺部(3.0%)。我们提出一例肺毛霉菌病和肺炎在Covid-19阳性患者带来尸检。该患者是一名正在受审的囚犯,被送往我们的设施接受治疗,据报告呈Covid阳性。
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Pneumonitis and Pulmonary Mucormycosis in a Covid-19 Positive Patient-A Case Report.

In the wake of second wave of coronavirus disease (Covid-19), an increased number of mucormycosis cases were reported by the Ministry of Health and Family Welfare in India. A total of 45 432 cases of mucormycosis were reported till mid-July 2021, with 4252 fatalities. Mucormycosis and other fungal infections are most commonly seen as an opportunistic infection. They are found in those with low underlying immunity either due to a diabetes, cancers particularly hematological malignancies, and so on, or as a side effect of prolonged/irrational use of certain drugs like steroids, immunosuppressive drugs for management of other disorders including Covid-19. The Health Authorities in India stated that although it is not a new disease, its true incidence during the beginning of the second wave was unknown as it was not a notifiable disease. As per reports, the most common presentations of mucormycosis included rhinocerebral (77.6%), cutaneous (4.3%), and pulmonary (3.0%). We present a case of pulmonary mucormycosis and pneumonitis in a Covid-19 positive patient brought for autopsy. The patient was an under trial prisoner sent for treatment to our facility who was reported Covid positive.

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来源期刊
Academic Forensic Pathology
Academic Forensic Pathology Medicine-Pathology and Forensic Medicine
CiteScore
0.90
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发文量
13
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