磁刺激和电刺激对大鼠周围神经损伤影响的比较研究。

A Bannaga, T Guo, X Ouyang, D Hu, C Lin, F Cao, Y Dun, Z Guo
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引用次数: 0

摘要

研究了脉冲磁刺激(MS)对坐骨神经损伤的影响。30 只大鼠被平均分为三组:MS 组(A)、电刺激(ES)组(B)和对照组(C)。在坐骨神经压迫 10 分钟后立即施加 MS 和 ES。实验后测量坐骨神经功能指数(SFI)、趾展反射(TSR)、肌肉重量和体积。A 组和 B 组的 TSR 发生在第 4 天,而对照组的 TSR 发生在第 10 天。A 组和 B 组的 SFI 差异有统计学意义(P < 0.01)。据统计,A 组和 B 组的腓肠肌重量和体积均大于对照组(P < 0.01)。MS 的效果与 ES 相似。这表明,在神经损伤后立即应用 MS 可加快功能恢复,防止或减少肌肉萎缩,因此具有重要的临床价值。该技术操作简便、无创伤、无痛苦,可承受高强度输出。
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A comparative study of the effects of magnetic stimulation and electric stimulation on peripheral nerve injury in rat.

The influence of pulsed magnetic stimulation (MS) on the sciatic nerve injury was investigated. Thirty rats were divided into three groups equally: MS group (A), electric stimulation (ES) group (B) and the control group (C). The MS and ES were applied immediately after the first 10 min of the sciatic nerve crush. Sciatic function index (SFI), toe spreading reflex (TSR), muscular weight and volume were measured after the experiment. The TSR of in the groups A and B occurred at 4th day while in the control group it occurs at 10th day. There was statistically significant difference in SFI between groups A and B (P < 0.01). The weight and volume of the gastrocnemius muscle were statistically greater in the groups A and B than in the control group (P < 0.01). The effect of MS was similar to that of ES. It was suggested that the application of MS immediately after the nerve injury might have an important clinical value as it can accelerate functional recovery and prevent or minimize muscle atrophy. The technique is easily to operate, non-invasion, painless and permits tolerance of high intensity output to be used.

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