引起46天大婴儿肺部感染和肝功能障碍的一种罕见病原体:放射性根瘤菌。

IF 1.4 4区 医学 Q3 PEDIATRICS Paediatrics and International Child Health Pub Date : 2022-08-01 Epub Date: 2023-03-13 DOI:10.1080/20469047.2023.2188383
Yanyan Wang, Shuhua An
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引用次数: 0

摘要

根瘤菌辐射杆菌是一种需氧、能动、氧化酶阳性、非孢子形成的革兰氏阴性致瘤植物病原体,很少感染人类。一名46天大的女孩因发烧和咳嗽10天而入院。她因感染放射杆菌而患肺炎和肝功能不全。3之后 在接受头孢曲松(复方甘草甜素和氨溴索)治疗几天后,她的体温恢复正常,肺炎有所好转,但肝酶水平继续升高。在美罗培南(甘草甜素和还原型谷胱甘肽)治疗后,她的病情稳定,没有肝损伤,15岁后出院 天。R.radiobacter毒力低,抗生素高度敏感,但在脆弱的儿童中,很少会发生严重的器官功能障碍并导致多系统损伤。
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A rare pathogen causing pulmonary infection and liver dysfunction in a 46-day-old infant: Rhizobium radiobacter.

Rhizobium radiobacter is an aerobic, motile, oxidase-positive, non-spore-forming Gram-negative tumorigenic plant pathogen which rarely infects humans. A 46-day-old girl was admitted to hospital with a 10-day history of fever and cough. She had pneumonia and liver dysfunction owing to infection by R. radiobacter. After 3 days of treatment with ceftriaxone, (compound glycyrrhizin and ambroxol), her body temperature returned to normal and the pneumonia improved, but liver enzyme levels continued to rise. After treatment with meropenem (glycyrrhizin and reduced glutathione), her condition stabilised and she recovered with no liver damage, and was discharged after 15 days. R. radiobacter has low virulence and antibiotics are highly sensitive, but, rarely, severe organ dysfunction can occur and result in multi-system damage in vulnerable children.

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来源期刊
CiteScore
3.30
自引率
0.00%
发文量
19
审稿时长
6-12 weeks
期刊介绍: Paediatrics and International Child Health is an international forum for all aspects of paediatrics and child health in developing and low-income countries. The international, peer-reviewed papers cover a wide range of diseases in childhood and examine the social and cultural settings in which they occur. Although the main aim is to enable authors in developing and low-income countries to publish internationally, it also accepts relevant papers from industrialised countries. The journal is a key publication for all with an interest in paediatric health in low-resource settings.
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