{"title":"引起46天大婴儿肺部感染和肝功能障碍的一种罕见病原体:放射性根瘤菌。","authors":"Yanyan Wang, Shuhua An","doi":"10.1080/20469047.2023.2188383","DOIUrl":null,"url":null,"abstract":"<p><p><i>Rhizobium radiobacter</i> is an aerobic, motile, oxidase-positive, non-spore-forming Gram-negative tumorigenic plant pathogen which rarely infects humans. A 46-day-old girl was admitted to hospital with a 10-day history of fever and cough. She had pneumonia and liver dysfunction owing to infection by <i>R. radiobacter</i>. After 3 days of treatment with ceftriaxone, (compound glycyrrhizin and ambroxol), her body temperature returned to normal and the pneumonia improved, but liver enzyme levels continued to rise. After treatment with meropenem (glycyrrhizin and reduced glutathione), her condition stabilised and she recovered with no liver damage, and was discharged after 15 days. <i>R. radiobacter</i> has low virulence and antibiotics are highly sensitive, but, rarely, severe organ dysfunction can occur and result in multi-system damage in vulnerable children.</p>","PeriodicalId":19731,"journal":{"name":"Paediatrics and International Child Health","volume":"42 3-4","pages":"161-164"},"PeriodicalIF":1.4000,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A rare pathogen causing pulmonary infection and liver dysfunction in a 46-day-old infant: <i>Rhizobium radiobacter</i>.\",\"authors\":\"Yanyan Wang, Shuhua An\",\"doi\":\"10.1080/20469047.2023.2188383\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><i>Rhizobium radiobacter</i> is an aerobic, motile, oxidase-positive, non-spore-forming Gram-negative tumorigenic plant pathogen which rarely infects humans. A 46-day-old girl was admitted to hospital with a 10-day history of fever and cough. She had pneumonia and liver dysfunction owing to infection by <i>R. radiobacter</i>. After 3 days of treatment with ceftriaxone, (compound glycyrrhizin and ambroxol), her body temperature returned to normal and the pneumonia improved, but liver enzyme levels continued to rise. After treatment with meropenem (glycyrrhizin and reduced glutathione), her condition stabilised and she recovered with no liver damage, and was discharged after 15 days. <i>R. radiobacter</i> has low virulence and antibiotics are highly sensitive, but, rarely, severe organ dysfunction can occur and result in multi-system damage in vulnerable children.</p>\",\"PeriodicalId\":19731,\"journal\":{\"name\":\"Paediatrics and International Child Health\",\"volume\":\"42 3-4\",\"pages\":\"161-164\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2022-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Paediatrics and International Child Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/20469047.2023.2188383\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/3/13 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Paediatrics and International Child Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/20469047.2023.2188383","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/3/13 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"PEDIATRICS","Score":null,"Total":0}
A rare pathogen causing pulmonary infection and liver dysfunction in a 46-day-old infant: Rhizobium radiobacter.
Rhizobium radiobacter is an aerobic, motile, oxidase-positive, non-spore-forming Gram-negative tumorigenic plant pathogen which rarely infects humans. A 46-day-old girl was admitted to hospital with a 10-day history of fever and cough. She had pneumonia and liver dysfunction owing to infection by R. radiobacter. After 3 days of treatment with ceftriaxone, (compound glycyrrhizin and ambroxol), her body temperature returned to normal and the pneumonia improved, but liver enzyme levels continued to rise. After treatment with meropenem (glycyrrhizin and reduced glutathione), her condition stabilised and she recovered with no liver damage, and was discharged after 15 days. R. radiobacter has low virulence and antibiotics are highly sensitive, but, rarely, severe organ dysfunction can occur and result in multi-system damage in vulnerable children.
期刊介绍:
Paediatrics and International Child Health is an international forum for all aspects of paediatrics and child health in developing and low-income countries. The international, peer-reviewed papers cover a wide range of diseases in childhood and examine the social and cultural settings in which they occur. Although the main aim is to enable authors in developing and low-income countries to publish internationally, it also accepts relevant papers from industrialised countries. The journal is a key publication for all with an interest in paediatric health in low-resource settings.