免疫学的贡献:免疫应答和限制

IF 0.7 4区医学 Q4 UROLOGY & NEPHROLOGY Nephrologie & Therapeutique Pub Date : 2023-06-12 DOI:10.1684/ndt.2023.27

Étienne Brochot

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引用次数: 0

摘要

在过去的50年里，疫苗接种领域的进展和免疫反应的探索为传染病的预防提供了积极的前景。然而，要提高广义上移植受者或免疫功能低下患者接种疫苗的有效性和安全性，还有很长的路要走。在这些人群中，疫苗接种的利益/风险平衡甚至比一般人群更为明显。因此，在这些人口中持续产生数据非常重要，但可能受到各种人力、技术和财政因素的干扰。在这篇文章中，我们将试图描述一些这些限制免疫应答接种及其探索，特别是在移植受者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Contribution of immunology: immune response to vaccination and limits

Advances over the past 50 years in the field of vaccination and the exploration of the immune response offer positive prospects for the prevention of infectious diseases. However, there is still a long way to go to improve the efficacy and safety of vaccination for transplant recipients or immunocompromised patients in the broad sense. In these populations, the benefit/risk balance of vaccination is even more pronounced in favor than that of the general population. Thus, consistently generating data in these populations is of great importance but can be disrupted by various human, technical and financial factors. In this text, we will attempt to describe some of these limitations for the immune response to vaccination and its exploration, especially in transplant recipients.

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来源期刊

Nephrologie & Therapeutique 医学-泌尿学与肾脏学

CiteScore

0.80

自引率

14.30%

发文量

485

审稿时长

11.9 weeks

期刊介绍： Organe d''expression de la Société de Néphrologie, de la Société Francophone de Dialyse et de la Société de Néphrologie Pédiatrique, Néphrologie et Thérapeutique a pour vocation de publier des textes en français dans le domaine de la Néphrologie, qu''il s''agisse d''actualisation des connaissances, de recommandations de bonne pratique clinique, de publications originales, ou d''informations sur la vie des trois sociétés fondatrices. La variété des thèmes abordés reflète la richesse de la Néphrologie, qu''il s''agisse d''aspects fondamentaux issus de la physiologie, de l''immunologie, de l''anatomo-pathologie, ou de la génétique, ou de sujets de néphrologie clinique, notamment ceux en rapport avec les thérapeutiques néphrologiques, transplantation, hémodialyse et dialyse péritonéale.

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