超声心动图在免疫检查点抑制剂治疗患者中的作用。

IF 1.4 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Echocardiography Pub Date : 2023-12-01 Epub Date: 2023-08-30 DOI:10.1007/s12574-023-00621-z

Kazuaki Tanabe, Junya Tanabe

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引用次数: 0

摘要

发生在心脏的免疫相关不良事件(心脏免疫相关不良事件;免疫检查点抑制剂(ICIs)引起的irAEs包括心肌炎、心律失常、传导障碍、心包疾病和takotsubo心肌病。心脏irae很少见，但会危及生命。在心脏肿瘤学中，最近对癌症治疗引起的心脏疾病的研究引起了人们的关注，这些研究可能阐明心脏irae的病理生理学并有助于制定治疗策略。本文综述了心脏irae的致病机制以及超声心动图在接受ICIs治疗的患者中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Role of echocardiography in patients treated with immune checkpoints inhibitors.

Immune-related adverse events occurring in the heart (cardiac immune-related adverse events; irAEs) by immune checkpoint inhibitors (ICIs) include myocarditis, arrhythmia, conduction disturbance, pericardial diseases, and takotsubo cardiomyopathy. Cardiac irAEs are rare but life-threatening. In cardio-oncology, the study of cardiac disorders caused by cancer treatment has recently attracted attention, and such studies may elucidate the pathophysiology of cardiac irAEs and contribute to management strategies. This review discusses the pathogenic mechanisms underlying cardiac irAEs and the role of echocardiography in patients treated with ICIs.

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来源期刊

Journal of Echocardiography CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

3.00

自引率

6.20%

发文量

期刊介绍： The Journal of Echocardiography, the official journal of the Japanese Society of Echocardiography, publishes work that contributes to progress in the field and articles in clinical research as well, seeking to develop a new focus and new perspectives for all who are concerned with this discipline. The journal welcomes original investigations, review articles, letters to the editor, editorials, and case image in cardiovascular ultrasound, which will be reviewed by the editorial board. The Journal of Echocardiography provides the best of up-to-date information from around the world, presenting readers with high-impact, original work focusing on pivotal issues.