covid -19感染后甲状腺疾病:新发自身免疫性甲状腺疾病1例报告。

IF 1.6 Q3 ALLERGY Asia Pacific Allergy Pub Date : 2023-03-01 DOI:10.5415/apallergy.0000000000000023
Anh Ngoc Trinh, Kim Han Nguyen, Dinh Van Nguyen
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引用次数: 0

摘要

我们报告了甲状腺功能亢进合并自身免疫性甲状腺疾病,这是在COVID-19感染后几周发生的,患者之前没有甲状腺疾病。我们的病例描述了临床表现、诊断测试和随后的患者管理,并与其他类似病例进行了比较。28岁女性,无甲状腺功能障碍史,感染新冠病毒后8周出现甲状腺功能亢进,促甲状腺激素低,游离甲状腺素4高,甲状腺受体抗体高。几周后甲巯咪唑20毫克治疗效果良好。我们检索了文献,发现了另外三个类似的报告病例,并进行了比较。COVID-19感染对免疫系统和甲状腺的影响可能解释了该患者COVID-19感染后甲状腺功能亢进的病理。新发甲状腺功能亢进症发现于一名症状轻微的妇女,对噻马唑和β受体阻滞剂反应良好。
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Thyroid disease post-COVID-19 infection: Report of a case with new-onset autoimmune thyroid disease.

We present hyperthyroidism with autoimmune thyroid disease, which developed a few weeks after the COVID-19 infection in a patient with no prior thyroid disease. Our case was described with clinical presentations, diagnostic tests, and subsequent patient management and compared to other similar reported cases. A 28-year-old female patient with no prior history of thyroid dysfunction developed hyperthyroidism 8 weeks after COVID-19 infection, confirmed by low thyroid stimulating hormone, high free thyroxine 4, and thyroid receptor antibody. She was treated and responded well to methimazole 20 mg in a few weeks. We searched the literature and found three other similar reported cases and compared those. The effects of COVID-19 infection on the immune system and the thyroid gland might explain the pathology of hyperthyroidism post-COVID-19 infection in this patient. This new-onset hyperthyroidism was found in a woman with mild symptoms and responded well to thiamazole and β-blockers.

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来源期刊
CiteScore
2.50
自引率
5.90%
发文量
33
期刊介绍: Asia Pacific Allergy (AP Allergy) is the official journal of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology (APAAACI). Although the primary aim of the journal is to promote communication between Asia Pacific scientists who are interested in allergy, asthma, and clinical immunology including immunodeficiency, the journal is intended to be available worldwide. To enable scientists and clinicians from emerging societies appreciate the scope and intent of the journal, early issues will contain more educational review material. For better communication and understanding, it will include rational concepts related to the diagnosis and management of asthma and other immunological conditions. Over time, the journal will increase the number of original research papers to become the foremost citation journal for allergy and clinical immunology information of the Asia Pacific in the future.
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